Salivary Gland Diseases Flashcards

1
Q

3 sub categories of salivary gland diseases

A

Reactive

Benign

Malignant

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2
Q

a lesion caused by the traumatic rupture of salivary ducts, resulting in the release of mucous into adjacent CT

A

mucous extravasation phenomenon

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3
Q

most common form of mucous extravasation phenomenon, a mucous-containing cystic lesion commonly found on the lower lip

A

mucocele

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4
Q

Depending on its size, mucoceles can appear blue because of 3 reasons:

A
  • tissue cyanosis
  • vascular congestion
  • translucency of underlying fluid

*Think: CCF

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5
Q

mucocele on the floor of the mouth

A

ranula (means frog’s belly)

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6
Q

tx for a mucocele

A

complete excision, must remove entire affected salivary gland or risk higher chance of recurrence

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7
Q

the same as the mucous extravasation phenomenon except this is a histologically true cyst (lined by epithelium)

A

mucous retention cyst

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8
Q

cause of a mucocele vs mucous retention cyst

A

Mucocele- trauma

Mucous retention cyst- blockage of salivary ducts by sialolith (calcified mass)

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9
Q

a rapidly expanding ulcerative lesion usually located towards the back of the hard palate, this condition is usually due to ischemic necrosis of minor salivary glands as a result of trauma or local anesthesia

A

necrotizing sialometaplasia

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10
Q

cause of necrotizing sialometaplasia

A

ischemic necrosis of minor salivary glands as a result of trauma or local anesthsia

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11
Q

tx for necrotizing sialometaplasia

A

self heals in 6-10 weeks

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12
Q

a hyperimmune multi-systemic disease with rare oral involvement that affects salivary glands and mucosa, this condition may be triggered by mycobacteria (the primary etiology of TB) and is therefore primarily a pulmonary disease

A

sarcoidosis

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13
Q

bacteria that may trigger sarcoidosis

A

mycobacteria, the primary etiology of TB

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14
Q

oral manifestation of sarcoidosis

A

xerostomia

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15
Q

2 conditions linked to sarcoidosis:

A

Lofgren’s syndrome- arthritis, bilateral hilar lymphadenopathy, and erythema nodosum

Heerfordt’s syndrome- anterior uveitis, parotid gland enlargement, facial nerve palsy, and fever

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16
Q

tx of sarcoidosis

A

corticosteroids

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17
Q

syndrome characterized by arthritis, bilateral hilar lymphadenopathy, and erythema nodosum

A

Lofgren’s syndrome

18
Q

syndrome characterized by anterior uveitis, parotid gland enlargement, facial nerve palsy, and fever

A

Heefordt’s syndrome

19
Q

cyst caused by the blockage of glands in the sinus mucosa, can only be observed radiographically, appears as a bump along the base of the sinus floor

A

sinus retention cyst (aka antral pseudocyst)

20
Q

tx for sinus retention cyst

A

none needed

21
Q

an autoimmune disease affecting salivary and tear glands, leading to dry mouth and eyes

A

Sjogren’s syndrome

22
Q

Two stages of Sjogren’s syndrome:

A

Primary- characterized by keratoconjunctivitis sicca (dry eye) and xerostomia (dry mouth)

Secondary- same as primary + another autoimmune disease (usually RA, which typically involves TMJ disorders)

23
Q

antibodies common in Sjogren’s syndrome patients

A

ANA (antinuclear antibody)
RF (rheumatoid factor)
SSA (Sjogren syndrome A)
SSB (Sjogren syndrome B)

24
Q

a benign salivary gland tumor developing in the upper lip and parotid gland

A

monomorphic adenoma

25
this adenoma is composed of a single cell type, and includes basal cell adenoma, canalicular adenoma, myoepithelioma, and oncocytic tumor
monomorphic adenoma
26
tx of monomorphic adenoma
surgical excision
27
MC benign salivary gland tumor developing in the parotid gland (majority of cases) and submandibular gland
pleomorphic adenoma
28
this "mixed tumor" adenoma is composed of a mixture of cell types (CT and epithelial cells)
pleomorphic adenoma
29
clinically, this tumor can vary widely in size and has firm, rubbery swelling
pleomorphic adenoma
30
a benign cystic tumor composed of oncocytes, or epithelial cells with excessive number of mitochondria, and lymphoid cells
Warthin's tumor
31
common location of Warthin's tumor
parotid gland of older men
32
Malignant salivary gland lesions are primarily found where?
palate
33
a rare form of cancer that most commonly forms in salivary glands or other head/neck regions, but can also occur in other parts of the body (breast, skin, cervix)
adenoid cystic carcinoma
34
microscopically, a cribriform or Swiss cheese pattern of cells can be observed
adenoid cystic carcinoma
35
lethality of adenoid cystic carcinoma
high, 10% survival rate at 15 yrs
36
the MC salivary gland malignancy
mucoepidermoid carcinoma
37
these low-grade cancers are composed of mucosal and epithelial cells
mucoepidermoid carcinoma
38
2nd MC salivary gland malignancy
polymorphous low-grade adenocarcinoma (PLGA)
39
the prefix "adeno" of this malignancy refers to gland, and helps solidify the fact that this tumor is found almost exclusively in minor salivary glands
polymorphous low-grade adenocarcinoma (PLGA)
40