S52(7) Apergillosis Flashcards

1
Q

Aspergillus

A

voriconazole

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2
Q

Aspergillus Risk Factors

A

Prolonged neutropenia
Hematopoietic stem cell transplant (HSCT) aka bone marrow transplant (BMT)
Solid organ transplant (SOT)
Hematologic malignancy

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3
Q

β-1,3-D glucan

Present in the cell wall of Candida species, Aspergillosis, PCP, and Fusariosis

A

True

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4
Q

Diagnostic Review

A

Halo sign specific to Aspergillosis

Galactomannan - Specific to Aspergillosis

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5
Q

Aspergillosis Diagnosis

Culture

A

Bronchiolalveolar Lavage (BAL) recommended for pulmonary infection
Usually grow in 2-5 days
Special stains

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6
Q

Aspergillosis Diagnosis

CT Chest recommended for pulmonary infection

A
Halo sign
Air crescent 
Nodules
Wedge shaped infarcts
Ground glass opacity reflecting hemorrhage
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7
Q

Aspergillosis Diagnosis

1,3-β-D glucan is recommended in high risk populations

A

Aspergillus
Candidiasis
Fusariosis
PJP

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8
Q

Aspergillosis Diagnosis

Galactomannan recommended in certain populations

A

Sensitivity ~ 70%

Zosyn

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9
Q

Aspergillosis
Invasive pulmonary
First line: voriconazole

A

True

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