Aminopenicillins plus betalactamase inhibitors Flashcards
What are the aminopenicillins plus betalactamase inhibitors?
Ampicillin-sulbactam (Unasyn)
Amoxicillin-clavulanate (Augmentin)
What bugs do Ampicillin-sulbactam (Unasyn) and Amoxicillin-clavulanate (Augmentin) cover?
Gram positive
Gram negative
Anaerobes
Other
What other bugs do Ampicillin-sulbactam (Unasyn) and Amoxicillin-clavulanate (Augmentin) cover?
Pasteurella multocida
What Gram positive bugs do Ampicillin-sulbactam (Unasyn) and Amoxicillin-clavulanate (Augmentin) cover?
Streptococcus and Bacilli
What Gram positive streptococci do Ampicillin-sulbactam (Unasyn) and Amoxicillin-clavulanate (Augmentin) cover?
Group A Streptococci (GAS)
Group B Streptococci (GBS)
Streptococcus pneumoniae
Enterococcus faecalis when Susceptible
What Gram positive bacilli do Ampicillin-sulbactam (Unasyn) and Amoxicillin-clavulanate (Augmentin) cover?
Listeria monocytogens
What Gram negative bugs do Ampicillin-sulbactam (Unasyn) and Amoxicillin-clavulanate (Augmentin) cover?
Enterobacteriaceae (Gut)
Non-Enteric (Not Gut)
What Gram negative Enterobacteriaceae do Ampicillin-sulbactam (Unasyn) and Amoxicillin-clavulanate (Augmentin) cover?
Escherichia coli
Klebsiella pneumoniae
Proteus mirabilis
Acinetobacter (sulbactam is active not ampicillin)
What Gram negative non-enterics do Ampicillin-sulbactam (Unasyn) and Amoxicillin-clavulanate (Augmentin) cover?
Haemophilus influenzae (drug of choice)
Morexella catarrhalis
Kingella sp
What Gram negative Anaerobes do Ampicillin-sulbactam (Unasyn) and Amoxicillin-clavulanate (Augmentin) cover?
Gut Anaerobes
Oral Anaerobes
Propionibacterium acnes
What Gram negative Gut Anaerobes do Ampicillin-sulbactam (Unasyn) and Amoxicillin-clavulanate (Augmentin) cover?
Bacteroides fragilis
Clostridium (not difficile)
What Gram negative Oral Anaerobes do Ampicillin-sulbactam (Unasyn) and Amoxicillin-clavulanate (Augmentin) cover?
Peptostreptococcus
Fusobacterium necrophorum
Prevotella melaninogenica
