S1_L4: Blood Supply of the Brain Flashcards
What are the four arteries supplying the brain?
Two internal carotid arteries
Two vertebral arteries
TRUE OR FALSE: The normal cerebral blood flow is 50-60 ml/100 g of brain tissue per minute
True
Source: BRS Neuroanatomy, 6th; Snell’s Clinical Neuroanatomy, 8th
The internal carotid arteries account for what percentage of cerebral circulation?
80%
The vertebral arteries account for what percentage of cerebral circulation?
20%
The basilar artery is formed by the union of ___
Two vertebral arteries
The posterior cerebral artery is not branch of internal carotid artery. The posterior communicating artery is a branch of internal carotid artery.
A. First statement is correct
B. Second statement is correct
C. Both are correct
D. Both are incorrect
C. Both are correct
Where is the Circle of Willis located?
In the interpeduncular fossa at the base of the brain
Enumerate the 3 small arteries of the spinal cord
Posterior spinal arteries (2)
Anterior spinal artery (1)
An increase in (1)___ or (2)___ ion concentration in the cerebral circulation has the most powerful vasodilator influence on cerebral blood vessels.
- Carbon dioxide
- Hydrogen
Note: Reduction in oxygen concentration also causes vasodilation
What is the most important factor in forcing the blood through the brain?
Arterial blood pressure
What are the 3 factors that oppose the arterial blood pressure?
- Raised intracranial pressure
- Increased blood viscosity
- Narrowing of the vascular diameter
TRUE OR FALSE: Cerebral blood flow remains constant despite changes in general BP
True
What is the largest branch of the internal carotid artery?
Middle cerebral artery
What is formed by the tight junctions that exist between the endothelial cells in the capillary beds and serves to isolate the brain tissue from the rest of the body?
Blood—brain barrier
TRUE OR FALSE: Capillary blood supply to the brain is greater in the gray matter than in the white matter.
True
Reason: Because metabolic activity in the neuronal cell bodies in the gray matter is much greater than in the nerve processes in the white matter
Cerebral blood vessels are innervated by ____ nerve fibers and respond to norepinephrine.
Sympathetic postganglionic
TRUE OR FALSE: Autoregulation of the circulation is accomplished by compensatory lowering of the cerebral vascular resistance when the arterial pressure is decreased. The cerebral vascular resistance rises when arterial pressure is increased.
True
What is considered as the main factor contributing to cerebrovascular resistance?
The diameter of cerebral blood vessels