S11 NEuro Neural Control Effectors Flashcards
Motor neuron’s cell body is in the
ventral horn of the spinal cord
Neuromuscular junctions in skeletal muscle have what receptors and what neurotransmitters
nicotinic muscular receptors acetylcholine
turn of events leading to muscle contraction
Act released from axon terminal of motor neuron binds to motor end plate receptors elicits an end-plate potential, triggering action potential action potential propagates along the sarcolemma and down T tubules action potential triggers release of Ca from Sarcoplasmic reticulum Ca binds to troponin exposing myosin-binding sites cross bridge cycle begins (muscle fiber contracts)
intrafusal fibers of the spindle are of two types
nuclear bag and nuclear chain fibers Dynamic stretch reflexes mediated primarily by nuclear bag fibers (1a afferents; annulospiral endings) - nuclear region is broader, and the nuclei are arranged several abreast - Primary endings are selectively sensitive to the onset of muscle stretch but discharge at a slower rate while the stretch is maintained Static stretch reflexes mediated primarily by nuclear chain fibers (II afferents; flowerspray endings) - nuclei lined up in chains. - Secondary endings are less sensitive to the onset of stretch, but their discharge rate does not decline very much while the stretch is maintained.
Golgi organs detect
muscle tension
monosynaptic muscle reflex
one sensory neuron, one synapse and one motor neuron knee jerk: stimulate extensor muscle and inhibit the flexor (polysynaptic)
Pupillary light reflex and consensual response
Light is shined on right eye for example info travels through optic nerve to the right and left pretectal nuclei. the pretectal nuclei stimulate both sides of the eddinger-westphal nucleus even though the light was perceived only in the right eye the right and left sides of eddinger-westphal nuclei generate action potentials through the right and left oculomotor nerves, causing both pupils to constrict. post synaptic cell bodies in ciliary ganglia
excitation-contraction coupling. two types of smooth muscle in terms of organization
single-unit smooth muscle: operates like a single unit because of extensive gap junction connections. Varicosity: swellings that release NT. If u activate one part, all is activated. multi-unit: activate one and only one activated. More ability for fine control.
The phosphatidylinositol pathway in VSM
The phosphatidylinositol pathway in VSM