Diencephalon Flashcards

1
Q

initially, closure of the neural tube in this region forms

A

rhombencephalon (hindbrain)

Mesencephalon (midbrain)

prosencephalon (forebrain)

during week 4

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2
Q

during week five prosencephalon divides into

A

telencephalon and diencephalon

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3
Q

during week five rhombencephalon divides into

A

divides into telencephalon and metencephalon

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4
Q

diencephalon parts

A
thalamus (dorsal)
hypothalamus 
epithalamus
sub/ventral thalamus
metathalamus (medial or lateral geniculate nuclei)
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5
Q

Three major groupings for thalamic nuclei

A

specific, non-specific, reticular

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6
Q

Specific “relay nuclei”

A

auditory system: cochlear nuclei- inferior colliculus- MEDIAL geniculate

visual system: retina- LATERAL geniculate

Sensory system: Ventral Posterior nuclei (VOM (head/face) and VPL (body) receives info from: Medial lemniscus, spinothalamic tracts, trigeminothalamic tracts- primary sensory cortex

Motor system: cerebellum- red nucleus- Ventral Lateral; substantia nigra- basal nulcei- Ventral Anterior

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7
Q

non-specific “association” nuclei

A

anterior (cingulate gyrus)

dorsomedial (prefrontal and orbital cortex)- limbic system

dorsomedial, pulvinar, lateral dorsal, and lateral posterior: connected widely with other thalamic nuclei and cortex connections r reciprocal

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8
Q

medial geniculate nucleus function

A

auditory system

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9
Q

lateral geniculate nucleus

A

visual system

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10
Q

pulvinar

A

sensory integration

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11
Q

ventral posterior medial

A

sensory for face

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12
Q

ventral posterior lateral

A

sensory for body

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13
Q

ventral lateral nucleus

A

motor system- cerebellum

Rostral-> motor
Caudal-> somatosensory

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14
Q

ventral anterior nucleus

A

motor system- basal nuclei

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15
Q

anterior nucleus

A

limbic system

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16
Q

lateral dorsal nucleus

A

limbic system

17
Q

lateral posterior nucleus

A

sensory integration

18
Q

dorsomedial nulceus

A

limbic system

19
Q

midline nucleus

A

cortico arousal

20
Q

reticular nulceus

A

inhibit thalamic nucleus

21
Q

intralaminar

A

activate cortex (thalamic activation)

22
Q

acute clinical manifestations of thalamic lesions

A

disturbances of consciousness (esp. bilateral)

behavior and memory disorders

contralateral hypesthesia and anesthesia, paresthesias

contralateral hemiataxia

quadrantanopia

23
Q

thalamic pain

A

condition developed after deafferentation of thalamus.

24
Q

central pain

A

deafferentation anywhere along CNS part of pain pathway

first symptoms often include lack of sensation and tingling in opposite side of body

weeks to months later, numbness can develop into severe and chronic pain that is not proportional to an environmental stimulus- allodynia

25
Q

epithalamus

A

habenular nuclei

pineal gland

26
Q

habenular nulcei

A

input from limbic system, projects to septal nuclei- role in reward processing

27
Q

pineal gland

A

produces melatonin: induction of sleep, melatonin secretion suppressed by light

calcification typically seen in adults- useful radiological landmark, as it is a midline structure

most common pathology: tumors-> early puberty onset, midbrain compression