Diencephalon Flashcards
initially, closure of the neural tube in this region forms
rhombencephalon (hindbrain)
Mesencephalon (midbrain)
prosencephalon (forebrain)
during week 4
during week five prosencephalon divides into
telencephalon and diencephalon
during week five rhombencephalon divides into
divides into telencephalon and metencephalon
diencephalon parts
thalamus (dorsal) hypothalamus epithalamus sub/ventral thalamus metathalamus (medial or lateral geniculate nuclei)
Three major groupings for thalamic nuclei
specific, non-specific, reticular
Specific “relay nuclei”
auditory system: cochlear nuclei- inferior colliculus- MEDIAL geniculate
visual system: retina- LATERAL geniculate
Sensory system: Ventral Posterior nuclei (VOM (head/face) and VPL (body) receives info from: Medial lemniscus, spinothalamic tracts, trigeminothalamic tracts- primary sensory cortex
Motor system: cerebellum- red nucleus- Ventral Lateral; substantia nigra- basal nulcei- Ventral Anterior
non-specific “association” nuclei
anterior (cingulate gyrus)
dorsomedial (prefrontal and orbital cortex)- limbic system
dorsomedial, pulvinar, lateral dorsal, and lateral posterior: connected widely with other thalamic nuclei and cortex connections r reciprocal
medial geniculate nucleus function
auditory system
lateral geniculate nucleus
visual system
pulvinar
sensory integration
ventral posterior medial
sensory for face
ventral posterior lateral
sensory for body
ventral lateral nucleus
motor system- cerebellum
Rostral-> motor
Caudal-> somatosensory
ventral anterior nucleus
motor system- basal nuclei
anterior nucleus
limbic system
lateral dorsal nucleus
limbic system
lateral posterior nucleus
sensory integration
dorsomedial nulceus
limbic system
midline nucleus
cortico arousal
reticular nulceus
inhibit thalamic nucleus
intralaminar
activate cortex (thalamic activation)
acute clinical manifestations of thalamic lesions
disturbances of consciousness (esp. bilateral)
behavior and memory disorders
contralateral hypesthesia and anesthesia, paresthesias
contralateral hemiataxia
quadrantanopia
thalamic pain
condition developed after deafferentation of thalamus.
central pain
deafferentation anywhere along CNS part of pain pathway
first symptoms often include lack of sensation and tingling in opposite side of body
weeks to months later, numbness can develop into severe and chronic pain that is not proportional to an environmental stimulus- allodynia
epithalamus
habenular nuclei
pineal gland
habenular nulcei
input from limbic system, projects to septal nuclei- role in reward processing
pineal gland
produces melatonin: induction of sleep, melatonin secretion suppressed by light
calcification typically seen in adults- useful radiological landmark, as it is a midline structure
most common pathology: tumors-> early puberty onset, midbrain compression