Rx Drug Abuse Flashcards
Is tolerance to drugs the same as physical dependence?
no
What neurotransmitter is most implicated in the neurobiology of addiction?
dopamine
Is opioid withdrawal more dangerous than a barbiturate withdrawal?
no
Is taking a drug for a pleasurable or euphoric feeling misuse or abuse?
abuse
The progression of addictive disorders is faster in __
a. males
b. females
b. females
males are more likely to have drug problems
2 drugs with most dependence?
- tobacco
- alcohol
__ is reduction in response to drug after repeated administration
tolerance
PD effect
What is most common type of tolerance?
alcohol
__ is an increase in response with repetition of the same dose of drug.
sensitization/reverse tolerance
Stimulant __ may result from a sensitized response after long intermittent periods of use
psychosis
Physical dependence constitutes addiction.
a. true
b. false
b. false
does NOT constitute addiction, but often accompanies it
What is the only actual evidence of physical dependence?
withdrawal syndrome
Withdrawal syndrome symptoms do not imply misuse or addictive behavior.
a. true
b. false
a. true
__ is compulsive engagement in rewarding stimuli, despite adverse consequences
addiction
all additive stimuli are reinforcing and intrinsically rewarding
What neurotransmitter and brain area are ultimately responsible for addiction?
dopamine
nucleus accumbens
