Drug Screen Flashcards

1
Q

What is the most common assay method used for urine drug screens?

A

enzyme immunoassay (EI)

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2
Q

Should pseudoephedrine be included in a urine drug screen?

A

yes - amphetamine screen

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3
Q

Urine drug screen sample size?

A

> 30mL

split 30mL into two different containers

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4
Q

Urine drug test temperature?

A

90-100F

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5
Q

Urine drug test pH?

A

4.5-8.5

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6
Q

Which testing method is used for confirmation and takes more time?

A

gas chromatography mass spectrometry (GC-MS)

can still miss some drugs (hydromorphone)

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7
Q

6 things tested for per federal (DHHS) guidelines for the workplace?

A
  • marijuana
  • cocaine
  • opiates
  • PCP
  • amphetamines
  • methamphetamine
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8
Q

Urine drug screens do not currently test for what very potent synthetic opioid?

A

carfentanil

100x more powerful than morphine

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9
Q

Is carfentanil overdose responsive to naloxone?

A

no

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10
Q

Which SSRI can trigger as a benzo on a drug test?

A

sertraline

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11
Q

Which non-SSRI GAD drug can trigger a drug test?

A

bupropion

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12
Q

Which diabetic drug can trigger a drug test?

A

metformin

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13
Q

What antiviral can trigger a false positive?

A

efavirenz

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14
Q

Which two benzos are detected with EI assay?

A
  • nordiazepam

- oxazepam

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15
Q

Which two opioids are tested for on EI assay?

A
  • morphine

- codeine

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16
Q

The below can cause a false positive for what drug?

venlafaxine, O-desmethylvenlafaxine, ibuprofen, diphenhydramine, lamotrigine, zolpidem

A

PCP

17
Q

Can eating a poppy seed bagel cause you to fail a drug test?

A

yes

18
Q

Passive marijuana smoke or ingestion of hemp foods does not cause positive test.

a. true
b. false

A

a. true

19
Q

What is the detection window for heavy marijuana use?

A

30 days

20
Q

What is the detection window for daily marijuana use?

A

10 days

Single/occasional: 3 days
moderate 4-6/week: 5 days

21
Q

Naloxone should be used even if a urine drug screen is negative.

a. true
b. false

A

a. true

22
Q

How long can hair sample be stored?

A

indefinitely

23
Q

Hair must be blow dried and sample refrigerated for hair drug test.

a. true
b. false

A

b. false

Wet hair must be gently dried
refrigeration/freezing causes swelling and drug loss

24
Q

Hair sample segments should be __ to __ mm long

A

10, 30

25
Q

The hair detection levels for amphetamine and opiates is __ng/mg

A

0.2

26
Q

The hair detection levels for cannabinoids are __ ng/mg

A

0.1

27
Q

The hair detection levels for cocaine is __ ng/mg

A

0.5

28
Q

Hair tests have high sensitivity or specificity for amphetamines and opioids?

A

specificity

not very sensitive for these

29
Q

Hair tests have high sensitivity or specificity for marijuana?

A

sensitivity

great for detecting marijuana, but not very specific; lots of false positives

30
Q

A sensitivity of better than __ % is indicative of a good test?

A

95