RSI - Drugs Flashcards
Etomidate (Amidate)
Dose:
Onset and Duration:
Dose:
- Adult-0.2-0.6mg/kg over 30-60 seconds (1/2 dose with hypotensive or altered patients)
- Pediatric (>10)-0.2-0.6mg/kg IV over 30-60 seconds
Onset and Duration: Within 30 seconds; 3-5 minutes
Etomidate (Amidate)
Class:
MOA:
Class: Nonbarbiturate hypnotic; anesthesia inducing agent
MOA: Short-acting drug that acts at the level of the reticular activating system to produce anesthesia
Etomidate (Amidate)
Contraindications:
Considerations:
Contraindications: Hypersensitivity; labor and delivery
Considerations: Carefully monitor vital signs; effects may be enhanced when given with other CNS depressants. Use half dose in the elderly, or significantly altered or hypotensive patients. Use with caution in pediatrics.
Etomidate (Amidate)
Indications:
Side Effects:
Indications:
-Sedation for painful procedures
Side Effects:
-Nausea/vomiting; dysrhythmias; breathing difficulty; hypotension or hypertension; involuntary muscle movement
Ketamine (Kerala)
Dose:
Onset and Duration:
Dose:
- Analgesia Adult- 0.2mg/kg IV (Max 20mg) or -0.5mg/kg IV (Max 50mg)
- RSI Induction- 2mg/kg IV
- Excited Delerium - 2-4mg/kg IM (Max 400mg)
Onset: (IV-30 seconds) (IM-3-5min)
Duration: (IV-5-10min) (IM-12-25min)
Ketamine (Ketalar)
Class:
MOA:
Class: Nonbarbiturate anesthetic
MOA: Produces a cataleptic-like state in which the patient is dissociated from the surrounding environment. Low doses produce analgesia and modulate central sensitization, hyper Algeria and opioid tolerance. Reduces polysynaptic spinal reflexes.
Ketamine (Ketalar)
Contraindications:
Considerations:
Contraindications:
-Severe hypertension; hypersensitivity
Considerations:
-Should not be given to patients with kidney failure. Known drug of abuse.
Ketamine (Ketalar)
Indications:
Side Effects:
Indications:
-Pain control, RSI sedation and analgesia, excited delirium
Side Effects:
-Hypertension; increased heart rate; hallucinations; delusions
Rocuronium (Zemuron)
Class:
MOA:
Class:
-Neuromuscular blockade (Nondepolarizing)
MOA:
-Inhibits transmission of nerve impulses by competitively binding with cholinergic receptor sites, antagonizing the action of acetylcholine.
Rocuronium (Zemuron)
Dose:
Onset and Duration:
Dose:
- RSI Induction and post procedure maintenance
- 1 mg/kg IV IO
Pediatric Dose:
-1 mg/kg IV IO
Rocuronium (Zemuron)
Contraindications:
Considerations:
Contraindications:
-Patient not intubated; can’t intubate; can’t ventilate
Considerations:
-Always provide sedation prior to administration in responsive patients; Roc has no effect on pain or consciousness; effects may be shortened in patients receiving chronic anticonvulsant therapy
Rocuronium (Zemuron)
Indications:
Side Effects:
Indications:
-Maintenance of paralysis following intubation to assist ventilations; prevent shivering in induced hypothermia
Side Effects:
-Transient hypotension/hypertension; nausea/vomiting; dysrhythmias; bronchospasm
Succinylcholine (Anectine)
Dose:
Onset and Duration:
Dose: Adult and Pediatric
1-2mg/kg IV
Onset: Within 1 minute
Duration: 5-10 minutes
Succinylcholine (Anectine)
Contraindications:
Considerations:
Contraindications:
-Can’t intubate/can’t ventilate; burn or crush injury (>24-48 hours); history of malignant hyperthermia; acute rhabdomyolysis; skeletal muscle myopathies; hyperkalemia, myasthenia Bravia
Considerations:
-Always provide sedations prior to administration in responsive patients; Suc has no effect on pain or consciousness; may increase serum potassium levels
Succinylcholine (Anectine)
Indications:
Side Effects:
Indications:
-Facilitate intubation; terminate laryngospasm; muscle relaxation
Side Effects:
-Hypotension; respiratory arrest; bradycardia; dysrhythmias
