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LS MRPSYCH > RP > Flashcards

RP Flashcards

1
Q

what endocanniboids act on

endorphin
enkephalin
dynorphin

A

endorphin = mu
enkephalin -delta
dynorphin - kappa

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2
Q

mum leaves, no emotion when returns from kiddo

A

avoidant

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3
Q

provides guidance but not done alone

A

vygotsky
zone of proximal

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4
Q

clinician rated

A

HAMD

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5
Q

infradium

A

longer than 24 hour
e.g. menstrutation

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6
Q

prazocsin

A

PTSD
and BPH

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7
Q

low bioavability

A

poor absorption -lurasidone
wide distribution -chlorpromazine

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8
Q

brain organoid

A

2nd trimester

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9
Q

what to check in atoxemine

A

BP
as increases hr AND BP

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10
Q

what to check before aglomelatine use

A

liver function

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11
Q

rhodosporin responds to

A

blue light

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12
Q

what is esketamine

A

NMDA antagonist

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13
Q

duloxetine half life

A

12 hr

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14
Q

elevated maze in rats/mice

A

anxiety

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15
Q

preimpulsion test

A

weak pre-impulse
startle
reduction in startle in schizophrenia

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16
Q

temp regulation in hypothalamus

A

anterior -hypothermic
posterior -hyperthermic

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17
Q

propiomelanocortin is associated with

A

ACTH

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18
Q

top down vs bottom up

A

top down -guided by knowledge
bottom up-sensory first then build up perception

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19
Q

terbetazine

A

VMAT 2 !!

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20
Q

WHAT CAN nalaxone do

A

bypass placebo affect
inhibit it

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21
Q

catie study

A

tolerability - zupirasidone
effiacy -clozapine

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22
Q

psilocybin

A

5HT2A

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23
Q

difference between chimera and mosaic

A

chimera - mopre 1 zygote
mosaic - 1 zygote

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24
Q

what are examples of gottmann institution

A

moritifcation- loss of self
institutionalisation
betrayal -reported by family friends

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25
Q

memory loss and benzo receptor

A

alpha 1

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26
Q

onerioid

A

dream like state

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27
Q

diff between schizoid and schizotypal

A

schizotypal -magical thinking
schizo - indifferent to criticism

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28
Q

detouring

A

family dyanmic
against 1 fam member

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29
Q

ubiquitin

A

chr 17

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30
Q

receptor for pitloisant

A

HT3

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31
Q

punding

A

parkinson
sorting objects, items eccessively

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32
Q

which are unstable and stable temperaments

A

unstable -choleric , melancohilic
stable - sanguine and phlegamtic

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33
Q

what is token economy

A

behaviour suystem
behaviour reinforced with token (secondary refinrocement) and later echanged for rewards.

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34
Q

difference between retroactive and proactive

A

new info replaces old for retroactive i.e. old number replaced by new mobile number

proactive - old inteferes with new

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35
Q

contangion theory

A

hypootic influence
influenced by those arounf
echo -social media
hysterical covid 19

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36
Q

crowd theory

A

contagion
convergence - similarites from begnning
emergent norm - new trends emerge and spread i.e. ice bucket

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37
Q

four types of suicide

A

alutristic - social norms/rituals

egoistic - self indiivudalisim, excessive low integrayion

fatalistic suicide- control on the individual by society

anaomic -lack of guidance or regulations from system e.g. overwehlmed when winning lottery

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38
Q

VARIABLE RAITO
continous

A

most resistent e.g. gambling
easy to extinct
intermittent refinforcement -longest tto establish

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39
Q

what is mind in the eyes

A

by cohen
lots of sets of eyes
adutls with autism to depice emotional state

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40
Q

what is dihsinhibited social engagement disorder

A

inadequate child care
approaching adults indicrimminately, willingness to go with strangers , overly familar behaviours towards stranger

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41
Q

kleine defence mechanism

A

SIP DOG

Splitting
introjection
projective identification
denial
gransodity
omnipotence

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42
Q

what is paraminia

A

disorganised facial expressions

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43
Q

what is parathymia

A

inappropriateness of affect

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44
Q

delusion disorder

A

ICD 1 MONTH
DCSM - 3 MONTH

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45
Q

timing for gaming disorder

A

12 months

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46
Q

difference between vomiting and laxarive use

A

vomtiing - metabolic alkaosis

laxative use - sodium low, acidosis metabolic

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47
Q

most common type of ocd

A

contimatinion

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48
Q

ocd with genetic risk highest in 1st degree relatives

A

symmetry (also see with slowing)
ordering rituals

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49
Q

kade
kuhn
kline

A

cade -lithium
kuhn- inpramine
kline -MOAI iprazmid
kane -clozapine

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50
Q

lirhium tremor is

A

10hz

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51
Q

fine vs coarse temor

A

fine - long term
coarse -toxicity

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52
Q

difference between social and unsocial conduct disorder

A

presence of friends or not

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53
Q

child or adolesence

A

before or after 10 year old

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54
Q

impotence vs priapism

A

alpha. 1pripaism
impoetence alpha 2

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55
Q

doesnt pass BBB

A

doapmine
sertaonin
sulpride /amisulpride

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56
Q

passes BBB

A

levadopa

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57
Q

hallucinogens

A

impact seratonin

LSD pisbo DMT Mesocaline

agonist of 5HT2A

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58
Q

dissociative drugs

A

KETAMINE
PCP
DXM
NO

impacts glutamate
NDMA antagonist

59
Q

canniboid receptors

A

THC
CB1 AND CB2

60
Q

antidepressant by IM

A

fluxopenthixol
mood elevating

61
Q

buccal antidepressant

A

selegline and amtriplyline

62
Q

most adrengeic antidepressant

A

desimpramine

63
Q

most antihistamingeric

64
Q

rectal antidepressant

A

trazone
ipramine
amitryplline

65
Q

antidepressant prostatism in elderly

A

amitrprylline

66
Q

venlafaxine

67
Q

shortest half life antidepressant

A

fluvoxamine

68
Q

antidepressant in diabetes

A

setraline
duloxetine

69
Q

autoinhbition antidepressant

A

also anti cholingeric paroxetine

70
Q

antidepressant half lives

A

fluvoxamine 14 hour
paroxetine 21 hr
sertraline 26-36 hr
citalopram 33 hour
fluxoetine 7-15 days. 5.6 days

71
Q

which antidepressant impacted by smoking

A

duloxetine
also reduced levels with gastric bypass

72
Q

antidepressant best antiemetic

A

mirtazpine

73
Q

difference between amisulpride and sulpride

A

sulpride d2
amisulrpide d2/d3

74
Q

myocarditis clozapine montioring

A

oesphilia most reliable
trop most sensitive

75
Q

seizure and cloza
300
300-600
>600

dose

76
Q

benzo longest half life

77
Q

treatment for premature ejaculation

A

dapoxetine

78
Q

which anti depressants cause delayed ejuculation

A

citalopram
fluxotine

79
Q

retinal pigmentation

A

thirodidazine

80
Q

which meds with a meal >500 calories

A

lurasidone
ziprasidone

81
Q

decreased with food absroption

82
Q

amantadine used in

A

influenze
parkinsonism

83
Q

antiepeilpetic sith aggressive behaviour

A

levetiretam
vigabatrin
toperimate

84
Q

depo switching to oral

A

depo 3-6 month then go to oral once steady plasma level

85
Q

akathasia high with

A

HRAZ
haloperidol
risperidone
aripiprazole
ziprasidone

86
Q

steady state
lithium
clozapine
sodium val

A

5 days
2-3 days
2-3 days

87
Q

cocaine
methylphedinate
mdma

A

cocaine and methylphedinate - DAT

mdma blocks sert

88
Q

drug metabolism

cannabis chronci
cannabis occasional
herion
methadone
cocaine
ampjetamine
angel dust
benzo

A

cannabis chronic 30 days , ocassional 1-3 days
herion 1-3 days
methadone -up to 7 days
cocaine 2-4 days
amphetamiens 48 hours
angel dust -8 days
benzo 24 hour

89
Q

difficulty in gait initiation w/o tremors

A

normal pressure hydrocephalus

90
Q

what artery is affected in hemianiopia homogenous

91
Q

artery in quadrantopoia

92
Q

alexia without agraphia
proposgonosia
contralateral hemianopia
ipelsilateral cranial nerve deficit

93
Q

akinetic mutism

A

bilateral
ACA

94
Q

most sediating antidepressant

A

pareoxtine
anticholngeric

also short half life

95
Q

location for procedural and long term memory

A

LT memory - hippocampus
procedural - cerebellum

96
Q

default mode network

A

MAPPP
Medial prefrontal cortex
precuneus
medial, lateral and inferior Pareital lobe
posterior cingulate cortex
angular gyrus

97
Q

salience network

A

ACTS

anterior insula
dorsal anterior cingulate cortex
thalamus
straitum

98
Q

central executiv network

A

DIP

dorsolateral prefrontal cortex
intraparietal sulcus
posterior pareital cortex

99
Q

verbal and visual working memory parts of brain

A

verbal LEFT DLPC
visual right DLPC

100
Q

which encephalitis is associated with lung cancer

101
Q

how do you differential broca from transcortical motor

A

repetition is intact whereas lost in broca

102
Q

how do u differentiate transcortical sensory from wernikes

A

repetition intact !!!

103
Q

conduction aphasia

A

broca and wernike intact stuff but loss of repetition

104
Q

deep brain stimulation in
:

depression
ocd
parkinson
tourettes

A

depression: stimulate cingulate gyrus

OCD: anterior limb of internal capsules

parikinson - subthalamic nucleus and globus pallidus

tourettes: ventromedial

105
Q

trans cranial magnetic Stimulation

A

frontal left in depression

106
Q

difference between T1 and T2 MRI

A

T1 enhance fatty tissue
T2 -enhance signal of water

107
Q

what does PET scan use

A

11 c labelling
brain metabolism by tagging organic compounds

108
Q

what does MRS used

A

hydrogen and phosphate 31

109
Q

what does spect use

A

technietium 99
xenon 123 idoine 123
gamma rays

110
Q

dti looks at

A

myelination

111
Q

DAT scan looks at

A

dopamine transporter scan

112
Q

which class of antideprssant can cause noctural myoclonus

113
Q

which antidepressant associated with seizure

114
Q

which condition hypoperfusion of corpus collosum

115
Q

gertstmann syndrome affects

A

supramarginal area

116
Q

how to manage restless syndrome

A

levodpoa
ropinole
dopamine agonist

117
Q

pragmattism

A

jumbled sentences

118
Q

xanomeline works by

119
Q

hypersalvation in clozapine mechanism

A

m4 agonism
alpha 2 antagonism

120
Q

which meds do not interact with lithium

A

haloperidol
cloza

121
Q

what can wais be divided into

A

verbal -words
performance (pictures, shapes)

122
Q

what are dominant pareital lesions

A

RL diorientation
dyscalculia
agraphia
finger agnosia

123
Q

monoamine a AND B coded by which chromosome

124
Q

what happens to glutamate in alzehimers

125
Q

sigma receptors in

A

depression

126
Q

eeg changes in sleep

A

sleep stage 1 - theta waves
sleep stage 2 - k. and spinges
sleep stage 3 - delta <50%
sleep stage 4 - delta >50
rem sleep - saw tooth

127
Q

learning in gambling

observaton alone

A

variable ratio

modelling

128
Q

whats fahr syndrome

A

calcification of basal ganglia

129
Q

what is biswanger

A

slow decline in memory
subcortical
leukorossis
small vessel damage

130
Q

what is cyproterone

A

blocks testosterone

131
Q

rivastigamine is not affected by

A

renal impairment

132
Q

enactive theory of perceputal and mental imagery

A

action cycle

6 steps
SOA AGO

schemata
objects
action
affect
goals
others behaviour

133
Q

capriprazine

A

d2/d3 agonist
parital 5HT1A
5HT2A AND B antagonist

134
Q

ect reduces what

A

acetylcholine

135
Q

ikr potassium is coded by

136
Q

lG1nmdar encephalitis

137
Q

LG11

A

hyponatraemia

138
Q

d2 occupancy and sensitivity increased

A

occupancy -parkinson

sensitivity -tard dyskinesia

139
Q

what is seen on scan with lithium

A

thickening of grey matter

140
Q

deliquenscence what age

A

8 to 10 years

141
Q

what is seen in blood and urine with wilsons

A

reduced ceurloplasmin
reduced serum copper
incresed urinary copper

142
Q

mirror neurons in humans

A

inferior frontal gyrus

broca area

mirroring people

143
Q

lurasidone mechanism of action

A

5ht7
5ht2a
d2

LS MRPSYCH (17 decks)

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