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crash course quesitons Flashcards

1
Q

what is seen in anti nMDAR encephalitis

A
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2
Q

difference between GABA-A and GABA-B encephalitis

A

gaba- A more severe seizure (and is treatment resistant)
ataxia
stiff person sydrome

gaba b- memory issues, mood issues

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3
Q

which three antigen in autoimmune encephalitis

A

anti Hu
aNTI Ma
anti GAD

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4
Q

the intracelular autoimmune enxcephlaitis how do you differentiate

A

NMDA - oralfacial dyskinesia, female, viral like prodome prior, acute, rapid decline, reduced consciousness

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5
Q

what s seen with anti LG11

A

hyponatremia
olderpeople
facialbrachio dystonic seizure
short memory impairment

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6
Q

anti caspr2

A

autonomic distubrance
.e.
heart rate
BP istability
T2 falre in medial temporal

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7
Q

diagnostic for
encephalitis

A

elevated WCC and protein

CSF is where u find the antibodies

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8
Q

most common chemical in PET SCan
list the rest
what is used commonly too

A

N13 O15 F18 C11

F18 MOSTCOMMON

racloprde d2/d3 antagonist

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9
Q

diff between f AND P MRI

A

f -oxygen consumption
p -FLOW in capillaries

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10
Q

what is incubatio?

A

worsening fears over time

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11
Q

shorter version of WAIS

A

WASI
30-60 mins

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12
Q

difference between flat and blunting

A

flat - no emotion
blunting -reduced emotion

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13
Q

difference between smooth and rough ER

A

Smooth -lipid
rough -protein

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14
Q

what is seen in depression re: HPA

A

HPA
reduced response to dexamastherone
increase coristol
recovers with treatment
increase size adrenal gland

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15
Q

Heart block which anti depressant

A

amitrypline

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16
Q

gut reaction associated with

A

ventromedial prefrontal cortex

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17
Q

what is paraschzmezia

A

distortion of body

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18
Q

heuaotoscopy

A

dissocitvative state
self in different external observe

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19
Q

chr 8
chr 6

A

NRG1 -8

DTNBP1 -6

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20
Q

G72 WHICH CONDITION

A

Comt
VELOFACIAL

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21
Q

what is courtsey stigma

A

stigma attached to those associated with stigmatised person

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22
Q

felt stigma

A

shame
associated with stopping seeking help

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23
Q

enacted stigma

A

unfair treatment

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24
Q

rating results for divorce, death of spouse , marriage, martial separation

A

death of spouse -100
divorce 73
marital separation - 65
marriage
50
retirement 45

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25
Q

What is daT1 ASSOCIATED WITH

A

SLCGA3
ADHD

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26
Q

5 adhd genes

A

DRD4
DRD5
SNAP25
HTR1B
5HTT

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27
Q

who disocrvered term cocktail party

A

cherry

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28
Q

tresiman and broadbent

A

broadment- filter theory
tesiman -dictionary unit

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29
Q

age and fears

A

ADA 2-4 - alone, dark, animals

teens -DEP death, eocnomics, politics

<1. - Height, sepearaion, stranger

the rest e.g. bodily harm, illness, criticism, failure is from 6-12

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30
Q

codon for fragile x

A

cgg

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31
Q

federatia ataxia codons

A

GAA

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32
Q

clozapine neutropenia risk factors

vs

agranolcytosis

A

young (decrease by 17% per decade)
africian carribean (77 uncrease)
previously low WCC

agranoycltosis

female
asian

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33
Q

what increase seizure risk
antipsychoticn

A

clozapine

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34
Q

metallic taste is seen with

A

lithium
also zopiclone

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35
Q

ebstein anamoly
which valve

A

triscupid

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36
Q

what are alar and basal plate

A

senssory
and motor neuron associated with them

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37
Q

what type of ion channel are GABA A AND B

A

A (iontropic)
B (metabtropic)

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38
Q

wh

which rating scale is used for EPSE for antipsychotics

A

sampson angus

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39
Q

cartoid vs vertobasilar stroke

A

cartoid - hemiparesis,

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40
Q

resistant to antidepressant and cbt

A

sexual obbsessions/rituals and hoarding

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41
Q

medications acting on gaba A

A

diazepam
zopiclone

gaba B is baclofen

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42
Q

propanolol

A

beta 1. beta 2 adrenernic antagonist

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43
Q

medication causing restless leg syndrome

A

quietapine

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44
Q

personality type where person is detached and no interest in others

A

schizoid

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45
Q

what is dysthymia

A

depressive perstant
mood lasting 2 years most days

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46
Q

how long needed for diagnosis of shcizophrenia and adjustment disordee

A

1 month

adjustment is also 1 month but resolves within 6 month of termination of stressor

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47
Q

who termed bulimia

A

russell

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48
Q

what is not seen in schziotpyal

A

hallucinations

but had odd belief maybe delusions
schizoid personality

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49
Q

where is the precuneus and what does it do

A

it is in superior parietal lobe

associated with recollection and inregrates information relating to preceptio and episoic memory retrivsl snd responds to pain

associated with default mode network

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50
Q

what does default node network do

A

involved in day dreaming
ruminating
mind wandering

when awake nbut not focused
thinking about themself past planning future

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51
Q

other parts of brain involved with default mode network

A

infterior preital
poster cingulate
medial prefrontal

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52
Q

what is the equivalent of 10mg diazepam in….

tempazepam
oxemazepam
nitrapazeam
clonazepam
alprazelam
lorazepam

A

lorazapem 1mg
temezpam oxemazpam 20mg
nitramazepam 5mg

cloazepam alprezelam 0.5mg
chlordizoazpode -25mg

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53
Q

couvade

couvade syndrome

A

partner of pregnant petrson experiences a type of conversion

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54
Q

ectasy what happens to which neurotramsitter

A

doap
sertanine
drop
therefore depressive state
depencency is less than cannabis or ccocaine

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55
Q

which

which receptor in pregablin

A

GABA

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56
Q

what does dopamine inhibit

A

prolactin
and also acetyl cyclase

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57
Q

phencyclidine which receptor

A

glutumate

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58
Q

autoregulation receptor

A

5HT1B

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59
Q

which agonist is most selective of d2

A

amisulpride

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60
Q

genes associated with parkinson

A

LRKKK2
SNCA alpha syljhce

parkin
putatae kinase (PINK)

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61
Q

what shows on eeg DURING SLEEP

A

saw tooth

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62
Q

pseuofantacastica

A

lies
false
branhc of mauncshen

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63
Q

whats seen in sleep in PTSD

A

increase eye movement
sleep 1 stage more

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64
Q

low voltage fast waves

A

delirium tremens on eeg

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65
Q

hormones wise,
what increases risk of DVT

A

HRT
oestrogen

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66
Q

what should be monitoring with aglomelaitne

A

liver function 3 6 12 24 for toxicty

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67
Q

what Mh condition pregabln for

A

generalised anxiety disordser

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68
Q

what is a key properity for olanzapine

A

lipophilic

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69
Q

mania has to last how long

A

1 week

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70
Q

what three meds can cause hyponatremia

A

notriayllpine
lofepramine
moclobemide

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71
Q

b

biggest rf for vascular dementia

A

HTN

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72
Q

male pseudohermaphroditism

A

17 beta hydroyxysteroid dehyrodgenase

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73
Q

rf for adhd

A

PREMATURITY

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74
Q

WHAT DOES THE DIANGOSTIC INTERVIEW SCALE INCLUDE

A

CATCHMENT AREA

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75
Q

honos scale assessment

A

recovery and outcome in mental illness

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76
Q

repetition of last syllabis

A

logiclonia

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77
Q

accelration on it own self

A

carbmazepine

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78
Q

what is anima

A

the unconscious feminine of a man

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79
Q

nitrous oxide presrep

A

l arginine

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80
Q

astasia abasia

A

dissociative motor

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81
Q

frotteuistic

A

inappropriate sexual behaviour
pressing and rubbing

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82
Q

what antipsychotic reduces seizure teshold

A

haloperidol

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83
Q

ganser syndrome -

A

rare
dissossiative
approximate answer

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84
Q

atresixis

A

negative moyoclonus

seen with metabolic encephalitis

flapping hand

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85
Q

re

receptor regulting caffeine

A

adenosine

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86
Q

what supplies the
ceberebral hemisphere
cerebellum vermis
internal capcsule

A

IC -posterior cerebral
cerebrallar superior cerebral
vermis posterior inferior

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87
Q

agraphaesthesia
asterognosis
anosgonia

A
  1. inability letter or number scratched on one skin

inability to ecgonise by touch
inability one owns neurological deficiet

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88
Q

dressing apraxia
which lobe

A

non dominant pareital

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89
Q

what is found on neuron and not glilal cell

A

glutamix acid decarboxylase

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90
Q

drop attacks associated with

A

kleine levin sx

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91
Q

agranyocystotis

A

clozapine
olanzapine
mirtazapine

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92
Q

terbertazine whcih 3 conditions

A

tardive dyskinesia
huntingdon
tourettes

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93
Q

amantadine

A

NDMA

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94
Q

inspidius on plasma and urine

A

plasma raised
urine low

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95
Q

assessmen including hypocondriac.

A

minnesota

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96
Q

lithium on an ecg

A

WENKIBACK

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97
Q

stories made from pcitures assessment

A

thematic

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98
Q

eysenka personality

A

includes the OCEAN stuff

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99
Q

upper quadrantanpoia

A

temporal lobe damage

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100
Q

factors for late onset shizo

A

female
reduced neg symotoms
infrequrnt
formal thought disorder
prominent hallucinations
premorbid paranoid personality
social isolation
sensory impairment

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101
Q

silly euphoric

102
Q

witzelsukt

A

inappropriate jokes

103
Q

loss of ego boundary

104
Q

dream work

A

freud
unconscious thought into dream
manifest
what is recalled

105
Q

time for iconic and echoic memory

A

0.5 sec

2 second

106
Q

william tuke

A

george III
moral treatment
live in community

107
Q

risk factor for eating disorder

A

overprotectiveness
enmeshment
insufficient resolution skills

108
Q

which inhibit 2d6

A

paroexitne
duloxetine
fluxoetine

109
Q

paramnesia

110
Q

bateson

A

contradictory message to child
schizo

111
Q

tinted blue

A

cyanopsia

sildanifil

112
Q

acetylation in causian

A

60%
10-20% asian

113
Q

if a med slow aceytlation what happens to HL

A

increase half life

114
Q

s/e of

hydralazline
nitrazepem

A

lupus

hangoer

sulfazaline -gi UPSET

isonizid -neuropathy

115
Q

notch 3

116
Q

tranlycorpominine what is it

A

antidepressant
associated with dependence
MAOI b\

headache
diarhrhoea
nausea
anxiery
tsexual dysufctrion
urinary hestiancy

117
Q

triazolam

A

2 hour half life

118
Q

what is doapmine formed from

A

l tyrosine
L dopa

119
Q

MAOI to SSRI

A

2 week wait at least

120
Q

schizo
hyper and hypoperfusion

A

hypo -frontal love, anrerior cingulate gryu

hyperperfusion - cerebellum, brain stem thalamus

121
Q

paroxetine impact on skiin

A

photosensitivty
induce MH hallucinations

122
Q

progranulin

123
Q

theophylline on lithium

A

increase lithium level

124
Q

atypical depression

A

bupropion
nefazodone

125
Q

lamotrigine increases risk of what in pregnancy

A

cleft palate

126
Q

what is pruning

A

natural elimination of unecessary synapses

127
Q

crow hypothesis

A

assymetrical cerebral in for of torque
primary disrubance in psychosis

128
Q

balloon cells

129
Q

anterior occlusion

A

quadrapesis
akinetic mutism

130
Q

14 -3-3 proteiN

131
Q

flumazil gaba which

132
Q

triiodothyronine

A

associated with gene transcription

thryoid hormone stuf f

133
Q

aglomelatine receptor

134
Q

mirtazpine receptor

135
Q

ados is for

A

autism observational scale

136
Q

pyshcosis in depression

A

moderate or severe

137
Q

wing beating tremor

138
Q

rf for agranolcytosis with cloapine

A

female
older
asian

139
Q

furosmide on ecg

A

qtc prolongation

140
Q

neuropil vaculoation

A

cjd
spongform sacs

141
Q

vortiexene

142
Q

d2 epse affinity

143
Q

deep stimulation in OCD

A

internal capsule

144
Q

gesalt psycholog y

A

closure - imagining the gaps
similary - circle, sqyare into groups

proximiity-distances
continity - lines smoothest path
pragnaz - reduce to simplest

PCPCS

145
Q

g

gait in normal pressure hydrocephalus

A

magnetic foot

146
Q

flight of idea vs loosening association

A

flight ideas connected
loosening - not associated

147
Q

functonal hallucination

A

same sensory modality

148
Q

assimilation
segregation
integration
marginlisation

A

assimilation - reject old culture
segregation - reject new culture
integration -both
marginalisation - reject both

149
Q

susto

A

mexican emotional state of others

150
Q

qtc prolonged in overdose

A

bruoprionin (shortening)
meclmbamide

151
Q

panksepp emotions

panksepp emotions

A

7

rage
fear

grief

lust
care

seeking
play

152
Q

3 attachment stages with protes

A

protest
despair
detachment

153
Q

kubler ross

A

DABDA

Denial
anger
barganing
depression
acceptance

154
Q

parke and bowlby grief

A

shock and numb
yearning and search
dspair and disorganisation
reorganisaton and recovery

SYDR

155
Q

deductive reasoning

A

valid conclusions made

156
Q

LG11

A

faciobrachial seizure of fce and arm

157
Q

MOG

A

optic neuritis

158
Q

yerkes dodson

A

too high too low
arousal

159
Q

ARIAe

160
Q

ect

A

reduced n acetylaspartate

161
Q

mania which region

A

orbitofrontal cortex

162
Q

part of brain
for social judgement

A

supramarginal

163
Q

donepezil and which cytocrome

164
Q

alzhemer on MRI

A

enterhinal loss atrophy

165
Q

bi

bilateral amyldada damage

A

fear response absent

166
Q

antiepileptic causing behavioural changes

A

levitreram

167
Q

ocd ect target

A

ocd subthamalemic nucleus and int capsule

parkinson - pallidus, interna subthaml

168
Q

moa must not be with

A

SSRI
but also nasal decogesations

169
Q

retroacrive inteference

A

when new memories impede retrviral of old memories

170
Q

in system

cannbis
heroin
crack cocaine
angel dust/pheldicine

A

cannibis 4 weeks
heroin 1-3 days
crack 6-8 hours
angel dust 8 days

171
Q

which drug causes a crash fatigue after withdrawl

172
Q

ketamine causes

A

hallucinations
nystagmus
salivation

173
Q

herion causes

174
Q

aphempthamines

A

confident wakeful energy

but hunger, laethgay, emotional withdrawl

class b

175
Q

COCAINE CAUSES

176
Q

prochaska and diclemetes

A

precontenplation - not thought about change, no issue noticed

contemplation - accepts problem, pros and cons but not taken intention

preparation -intents for change, testing waters

action motification taking plce 3-6 months good

maintendance. sustained change

relapse - return to previous behaviour

177
Q

metamorphosis

A

change in reception of object

paraposia - face specfically
and autoparaprosia 0 own face

178
Q

circular casuality

triangulation

A

all they know passed on

grandma, mum , child

trianglulation child in between parents argument

179
Q

empathy

180
Q

SLC6A4.

p-gylocprotein

A

SERTRAONIN TRANSPORT

ABcB1 MDR1

181
Q

glutmate is released from

A

astrocytes

182
Q

gaba projtection into straitum

A

spiny neurons

183
Q

what is conrad 5 stage for

A

delusional psychosis

four primary: perception, mood, atmosphere and initution (out of blue)

Trema -mood change
Aophany -search for meaning
Anastrophe - height of psychosis

consolidation -new world with meaning formed

residuum - autisitic

184
Q

alcoholic wernickes is affected by

A

mamilliory body

185
Q

z drug act on

A

GABA A

omega 1 alpha 1 receptor

186
Q

blotting

A

SOUTH - DNA

NORTH - RNA

West -protein

South -devon –> DNA
noRth- RNA

187
Q

methdaone
burporhpine
nalaxone
naltreene

A

methadone - full mu agonist
burp - partia mui aoggnist
naloxone - mu atangonist
naltrexene mu antagonist - support absistence

188
Q

downs -father is associated with

A

robertisonian translcatio

189
Q

midbrain vs pons stroke

A

pons
face ipsilateral and contralateral body

midbrain -face and body contralateral and EYE PALSY (ipsilateral)

190
Q

soamtic cell mutaiton

A

doesnt necessarily pass to next gen

191
Q

mitgehen vs mitmachen

A

mitgehen (gentle pressure) is extreme of mitmachen

192
Q

angeloposiure lamp

193
Q

amphetamine
methadoine
cocaine in system

A

cocaine 2-3 days
ampetamine 48 hour
methadone 1 week 7 days

194
Q

intelligence in fragile x

A

genetic load
x dominant

195
Q

flocculbonodular lobe

A

cerebellum

196
Q

hexosamidisne A

A

tachy sac dx

197
Q

most powerful opoid peptide

A

dynorphin A

opoid peptidew

198
Q

africian plant like khat

A

cathionine

199
Q

carboxyel ester in depos

A

increase fat solubility
slower reelase

200
Q

episodes number of mania for diagnosis of rapid cycling

delusions

A

4 episodes in 12 montjhs

3 months delusions

201
Q

thaimine deficiency

A

thansketolase

202
Q

durkheim

A

lack of social cohesion

seratonin binding reduce
dbut sertraonn transport increase

203
Q

narcolepsy associated with

A

HLA-DR2
chr 6

204
Q

sensory of tongue

A

anterior 2/3 - facial

posterior1/3 9th cranial nerve glosphargyneal

205
Q

anorexia

A

low t3

LAXATIVE low nA

206
Q

benton test

A

10images 1 by one
copy from memory
visual mmemory

207
Q

splitting into

A

idealised
denigrated

208
Q

caprirprazine

A

72 to 96 hr

209
Q

angelman
infantile
syphilis
stroke
eeg

A

stroke -focal/regional
infantile - diffuse giant waves
syphilis - slow wavves
angel man - high 2-3 hzfrontal epipform

210
Q

neuroprotective dementia med

211
Q

referent power

A

characiamtic
personality
ability to nfluence due to leadership, loyalit,y friendship

212
Q

melatonin is made from

213
Q

Paraventricular nucleus makes

214
Q

pap lantos in

A

multisystem atrophy

215
Q

thematic discovered by

A

murray

stories pictuee

216
Q

parent
child
sibling

A

sibling -9
parent -6
child -13

217
Q

what covers the pituary gland

A

sellar diaphragm

218
Q

falx cerebi
falx cerebelli

A

cerebi- separates cerebral hemisphere

cerebelli - split two hemisphere of cerebellum L AND R

219
Q

tentorium cerebelli

A

cerebellium from occipital

tentorium bulbus -olfactory -smell sense

220
Q

greek warrior

A

wolf hishcoff
4p

221
Q

assessment for brain damage

A

hallstend raiten dalley

222
Q

1st medical ethics

A

adab al tabb

223
Q

escape conditioning

A

to stop something i.e. noise, crying, annoying thing

224
Q

microgila

A

15% of population
mesdermal
K monitoring
macrophages

225
Q

mandibular branch via

226
Q

multisystemi atrophy

A

parkinson
autonomic instability cerebrallar ataxia

227
Q

fensetatred c. septum pallidum

A

dementia
puglistica

228
Q

stimuli preparedness

A

exposure to something over time and generation so not scared
i.e cars and humans

229
Q

bitemporal hemionpia

A

pituary tumour

230
Q

social loafering

A

less effort in a group

231
Q

menache

A

stage 4 tanner

11 and 12 for female and male puberty

232
Q

x linked condiiton
mps11

A

hunter syndrome

233
Q

what are vitamin d ricket and neurofibromas 1-2

A

NFB1/2 autosomal dominant
vitamin d ricket - x linked

234
Q

voltage gated calcium channel

235
Q

pick dx

236
Q

what does hepatic mebabolism do

A

make med more water soluble

237
Q

retts

A

hand wringing
female ??

238
Q

klucy bucy associateds with

239
Q

deotology

A

doing good
without thinking of consequences

240
Q

metacentric
acrocentric

A

meta- equal p and q arm

acro -short p, long q

241
Q

gorwth spurt boys

A

tanner 3-4

242
Q

biphasic triphasic wave on eeg

A

cruektjacob disease

243
Q

weight gain

244
Q

eudonomia

245
Q

velofascial sdynrome associated with

A

schizophrenia

246
Q

occulomotor
trochear
abundcens

A

occulomotor =-

ptosis
pulls inwards, therefore lesion -> odown utwards
not impacted on light.

trochear - posterior mid brain ->
superior ortbital fissure – superior oblique - medial rotate eye (ABDUCTION)

lesion means up and in ward with lesion
vertical diplopia, cant look down,

abducens moves laterally - lat rectus therefore lesion means eye goes inwards

247
Q

risk factor for tardive dyskesnaia

A

affecive disorder as well

248
Q

transience

A

gradual forgetting

249
Q

tip of tongue

A

Lethologica

250
Q

bandura

A

social learning theory

behavioru personal factor and envorment all interact

LS MRPSYCH (17 decks)

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