Routes of Administration

Question 1

Metabolic BW Formula

Answer 1

• kg^.765

- used for calculating the dose in different animal species (mg/kg BW)

Question 2

Which route of administration resembles IM, but is more variable and less reliable?

Answer 2

• subcutaneous administration

Question 3

Which route of administration can you find differences in bioavailability depending on the injection site?

Answer 3

• Intramuscular administration

Question 4

This route of administration has volume restrictions

Answer 4

• intramuscular

Question 5

Which route of administration avoids the first pass effect?

Answer 5

• topical administration

Question 6

If you needed to give large amounts of a drug what route of administration would you use?

Answer 6

• subcutaneous administration

Question 7

Which can you predict using the allometric scale pharmacokinetics or pharmacodynamics?

Answer 7

• pharmacokinetics

Question 8

____ is the correlation between pharmokinetics and metabolism/elimination

Answer 8

• Allometric Scaling = elimination/clearance

Question 9

What route of administration is intra-articular?

Answer 9

• local

Question 10

____ is the correlation between pharmokinetics and metabolism/elimination

Answer 10

• Allometric Scaling = How much of a drug is eliminated per min/kg

Question 11

Which route of administration can be local or systemic depending on gastrointestinal absorption?

Answer 11

• enteral (oral/rectal)

Question 12

Drug elimination is correlated with the ________

Answer 12

• cardiac output

- except for drugs showing rapid metabolism

Question 13

What route of administration provides slow prolonged absorption?

Answer 13

• subcutaneous