Excretion

Question 1

Herbivores with an alkaline urinary pH have a delayed elimination of drugs with a high/low pKa?

Answer 1

• high pKa

Question 2

pH of mastitis is ____ and favors excretion of ______ acidic/alkaline compounds

Answer 2

• 7.2

- acidic

Question 3

Glucose clearance

Answer 3

• No glucose excreted

- > filtered and absorbed

Question 4

Carnivores with an acidic urinary pH have a delayed elimination of drugs with high/low? pKa

Answer 4

• low pKa

Question 5

Renal Clearance

Answer 5

1. Glomerular Filtration - passive diffusion
2. Tubular secretion - active transport
3. Tubular reabsorption - passive or active

Question 6

Largely determined by glomerular filtration

Answer 6

• renal clearance

Question 7

Penicillin clearance

Answer 7

• more penicillin is excreted in urine than was filtered

Question 8

Urea clearance

Answer 8

• 50% of urea excreted

- > not all filtered is eliminated

Question 9

pH of milk is ____ and favors excretion of ______ acidic/alkaline compounds

Answer 9

• 6.6

- alkaline

Question 10

Non-absorbed drug fraction after oral administration

Answer 10

• non-renal clearance of drugs