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3 Micro > RNA viruses I > Flashcards

RNA viruses I Flashcards

1
Q

Major cause of laryngotracheobronchitis

A

PIV

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2
Q

Koplik spots

A

Measles (rubeola)

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3
Q

Influenzaviruses are all classified under

A

Orthomyxovirus

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4
Q

Red spots on buccal mucosa and descending maculopapular rash (head to toe). Fever persists throughout. Cough and coryza.

A

Measles

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5
Q

PIV subtype associated with bronchitis and pneumonia in infants and children

A

PIV 3

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6
Q

High fever, headache, muscle pain, red/itchy eyes –> chest pain, shock, blindness and bleeding

A

Severe hemorrhagic fever caused by filovirus

ebola/marburg

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7
Q

RNA virus with neuraminidase and hemagglutinin

A

Influenza A and B

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8
Q

PIV subtype most commonly causing croup

A

PIV 1 & 2

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9
Q

HDV requires this helper

A

HBV

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10
Q

Clinical manifestations of influenza in youth and elderly differ how?

A

More toxic-looking.

Otitis media, more GI symptoms, febrile convulsions, croup

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11
Q

Transmission of PIV

A

respiratory droplets or nasopharyngeal secretions

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12
Q

RSV uses these glycoproteins

A

G –> attachment

F –> fusion

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13
Q

RNA virus spread by mouse

A

Lymphocytic choriomeningitis virus (LCMV)

also lassa virus (both are arenaviruses)

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14
Q

Bunyaviruses have ARTHROPOD vectors except for

A

Hantavirus

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15
Q

Measles is highly contagious in this period

A

prodrome (pre-rash)

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16
Q

Treatment for laryngotracheobronchitis

A

racemic epinephrine aerosol

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17
Q

Most contagious period for mumps:

A

1-2 days before swelling

18
Q

Transmission of Hantavirus

A

Rats/rodents shed virus.

Humans inhale or have direct contact with particles. Or get bitten.

19
Q

Marburg and Ebola are both part of which family?

A

Filovirus

non-seg
enveloped

20
Q

Mumps symptoms:

A

Parotitis
Orchitis
Meningitis (aseptic)

21
Q

Fatal form of measles with confluent hemorrhagic skin eruptions

A

Black measles

22
Q

Negative-stranded RNA viruses:

A

ABOOFR = Always Bring Polymerase Or Fail Replication
(negative-sense viruses need polymerase to transcribe neg to positive strand)

Arena
Bunya
Paramyxo
Orthomyxo
Filo
Rhabdo
23
Q

Segmented viruses:

A 
(all RNA viruses)
BOAR
Bunya
Orthomyxo
Arena
Reo
24
Q

Picornavirus subfamilies

A 
PERCH
Polio
Echo
Rhino
Coxsackie
Hep A
25
Q

All picornaviruses are enteroviruses (feco-oral) except:

A

Rhinovirus

26
Q

Seal-like barking cough is called

A

Croup

27
Q

Hemorrhagic fever and biohazard agent.

A

Marburg

Ebola

28
Q

Biphasic illness:

Prodrome with vague symptoms: fever, headahe, lower myalgia, cough

Then abrupt cardiopulmonary phase (thrombocytopenia, hypoalbuminemia may be seen)

A

Hanta virus pulmonary virus

29
Q

Surface glycoprotein of influenza required for attachment of infecting virus to host-cell membrane

A

HA Hemagglutinin

30
Q

Surface glycoprotein of influenza required for release of virus from infected cells

A

NA Neuraminidase

31
Q

Horse, swine, birds are naturally infected by

A

Influenza A

32
Q

RNA virus that causes bronchiolitis and/or pneumonia commonly in children/babies

A 
#1 RSV
#2 Metapneumovirus

Both are Paramyxoviruses

33
Q 
Symptoms:
Anxiety
Radicular pain
Dysesthesia
Dysautonomia
Paralysis
Hydrophobia
A

Rabies

34
Q

High fever with myalgia, eye symptoms, thrombocytopenia
Hypotension
Oliguria
Convalescence

A

HFRS

fever with bleeding (thrombocytopenia) and renal problems

35
Q

Rabies PostEP Category 1

A

Contact with infected animal

Vaccine - no
RIG - no

36
Q

Rabies PostEP Category 2

A

Superficial scratch

Vaccine - yes
RIG - no

37
Q

Rabies PostEP Category 3

A

Transdermal bite/scratch

Vaccine - yes
RIG - yes

38
Q

Hemorrhagic fever with renal syndrome / HFRS is caused by

A

Hanta virus

39
Q

Uncommon progressive CNS manifestation in a persistent measles infection

A

Subacute sclerosing panencephalitis

40
Q

Basis for antigenic shift or drift among influenza types

A 
3 HA types (H1, H2, H3)
2 NA (N1, N2)
41
Q

Implies minor change in antigen without change in subtype.

A

Antigenic drift

42
Q

Major change in either or both antigens AND change in subtype. Causes outbreaks and pandemics

A

Antigenic shift

3 Micro (9 decks)

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