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3 Micro > DNA viruses > Flashcards

DNA viruses Flashcards

1
Q

Single-stranded, non-enveloped DNA virus

A

Parvovirus

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2
Q

Transmission from sharing toothbrush or razor associated with this DNA virus

A

HBV

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3
Q

Transmission of CMV?

A

contact with secretions:
Horizontally
Vertically
Blood transfusions

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4
Q

Polyomavirus target population:

A

immunocompromised

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5
Q

DNA virus that causes “slapped cheeks” appearance?

A

Parvovirus B19

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6
Q

Causes benign flesh-colored dome lesions with central dimple

A

Molluscum contagiosum virus (type of Poxvirus)

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7
Q

HBV antigen secreted into serum

A

e Antigen

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8
Q

Erythema infectiosum / fifth disease

A

Parvovirus B19

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9
Q

DNA virus that causes progressive multifocal leukoencephalopathy (PML)

A

JCV (polyoma)

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10
Q

DNA virus that causes pneumonia and other respiratory illnesses (colds, tonsilitis, ARDS, etc.)

A

Adenovirus

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11
Q

DNA virus that causes AIDS colitis, AIDS retinitis (also transplant recipients)

A

CMV (HHV-5)

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12
Q

DNA virus that causes Condyloma acuminata

A

HPV 6 and 11

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13
Q

Kaposi’s sarcoma

A

HHV-8 (KSHV)

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14
Q

Most common cause of acute hemorrhagic cystitis

A

Adenovirus

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15
Q

Polyoma virus that causes hemorrhagic cystitis

A

BKV

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16
Q

Only DNA virus that causes Hepatitis

A

HBV

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17
Q

Highly associated with congenital defects (primary maternal infection acquired during first half of gestation)

(other than HSV)

A

CMV (HHV-5)

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18
Q

Genital lesions are caused by this herpesvirus

A

HSV-2

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19
Q

DNA virus that causes RBC destruction in intrauterine infection –> Hydrops fetalis

A

Parvovirus B19

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20
Q

Clinical course of erythema infectiousum rash

A

trunks to extremeties

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21
Q

Initial HPV infection occurs in

A

basal keratinocyte

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22
Q

Causes chickenpox and zoster

A

Varicella-Zoster virus (HHV-3)

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23
Q

Associated with Hodgkin’s lymphoma

A

EBV (HHV-4)

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24
Q

Transmission of Parvovirus B19

A

respiratory droplets

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25
Q

Common warts

A

HPV 2 and 4

26
Q

Diseases caused by HHV-7

A

Clinically insignificant

27
Q

Polyoma virus that infects man and monkey

A

SV40

28
Q

Complication of zoster

A

Postherpetic neuralgia (pain after rash heals which persists for up to months/years)

29
Q

Epidermodysplasia verruciformis

A

HPV 5 and 8

30
Q

This virus lyses the oligodendroglia causing destruction of cerebral white matter in patchy distribution

A

JCV (polyoma virus)

31
Q

Complications of this infection include bacterial superinfection of skin, lungs, or bones by S. aureus or Group A strep.

A

Varicella (HHV-3)

32
Q

Causes smallpox

A

Variolavirus

33
Q

HBV nucleocapsid antigen

A

c Antigen

34
Q

Associated with Burkitt’s lymphoma

A

EBV (HHV-4)

35
Q

Causes Roseola infantum (exanthem subitum)

A

HHV-6

36
Q

DNA virus that causes mononucleosis

A

EBV (HHV-4)

CMV (HHV-5) causes a mononucleosis-like illness

37
Q

DNA virus that causes pruritic rash of red papules –> vesicles on stomach, back, face (scalp to trunk to extremities)

A

VZV (HHV-3)

38
Q

Causes Kissing Disease

A

EBV (HHV-4)

aka infectious mononucleosis

39
Q

Causes watery conjunctivitis

A

Adenovirus

40
Q

Causes oral lesions, along with spontaneous temporal lobe encephalitis, keratoconjunctivitis

A

HSV-1

41
Q

“milkmaid’s blisters”

Cowpox

A

Vacciniairus

used in vaccine that eradicated smallpox

42
Q

High-grade fever –> resolves –> appearance of maculopapular rash

A

Roseola infantum (HHV-6)

43
Q

Transmission of VZV

A

Varicella is airborne

44
Q

HBV antigen providing protection

A

s Antigen

45
Q

Associated with nasopharyngeal cancer

A

EBV (HHV-4)

46
Q

Infection involves localized unilateral vesicular skin eruptions along 1-3 dermatomes

A

Zoster (shingles)

47
Q

Fever, lymphadenopathy, exudative pharyngitis, atypical lymphocytosis are clinical manifestations

A

EBV (HHV-4)

48
Q

Causes aplastic crisis in G6PD-D, sickle cell, thalassemia

A

Parvovirus B19

49
Q

Associated with cervical and anogenital cancers

A

HPV 16 and 18

50
Q

macular, papular, vesicular, pustular rashes –> crusts

A

Smallpox

51
Q

Treatment of smallpox

A

methisazone, convalescent smallpox serum, vaccinia immuneglobulin

52
Q

Treatment of CMV

A

ganciclovir

53
Q

Treatment of EBV

A

supportive, short-course corticosteroids with inflammation

54
Q

Treatment for HBV

A

Interferon, lamivudine

55
Q

Treatment of polyomavirus

A

no specific treatment

56
Q

Treatment of parvovirus B19

A

supportive, analgesic

57
Q

Treatment of HPV

A

excision

58
Q

Treatment of adenovirus

A

ribavarin and cidofovir (usually in immunocompromised)

59
Q

Treatment of Herpes simplex

A

acyclovir

supportive

60
Q

Treatment of Varicella

A

IV acyclovir

61
Q

Cowdry A inclusions

A

HSV

62
Q

B cell latent

A

EBV

3 Micro (9 decks)

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