DNA viruses Flashcards

1
Q

Single-stranded, non-enveloped DNA virus

A

Parvovirus

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2
Q

Transmission from sharing toothbrush or razor associated with this DNA virus

A

HBV

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3
Q

Transmission of CMV?

A

contact with secretions:
Horizontally
Vertically
Blood transfusions

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4
Q

Polyomavirus target population:

A

immunocompromised

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5
Q

DNA virus that causes “slapped cheeks” appearance?

A

Parvovirus B19

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6
Q

Causes benign flesh-colored dome lesions with central dimple

A

Molluscum contagiosum virus (type of Poxvirus)

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7
Q

HBV antigen secreted into serum

A

e Antigen

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8
Q

Erythema infectiosum / fifth disease

A

Parvovirus B19

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9
Q

DNA virus that causes progressive multifocal leukoencephalopathy (PML)

A

JCV (polyoma)

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10
Q

DNA virus that causes pneumonia and other respiratory illnesses (colds, tonsilitis, ARDS, etc.)

A

Adenovirus

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11
Q

DNA virus that causes AIDS colitis, AIDS retinitis (also transplant recipients)

A

CMV (HHV-5)

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12
Q

DNA virus that causes Condyloma acuminata

A

HPV 6 and 11

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13
Q

Kaposi’s sarcoma

A

HHV-8 (KSHV)

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14
Q

Most common cause of acute hemorrhagic cystitis

A

Adenovirus

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15
Q

Polyoma virus that causes hemorrhagic cystitis

A

BKV

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16
Q

Only DNA virus that causes Hepatitis

A

HBV

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17
Q

Highly associated with congenital defects (primary maternal infection acquired during first half of gestation)

(other than HSV)

A

CMV (HHV-5)

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18
Q

Genital lesions are caused by this herpesvirus

A

HSV-2

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19
Q

DNA virus that causes RBC destruction in intrauterine infection –> Hydrops fetalis

A

Parvovirus B19

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20
Q

Clinical course of erythema infectiousum rash

A

trunks to extremeties

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21
Q

Initial HPV infection occurs in

A

basal keratinocyte

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22
Q

Causes chickenpox and zoster

A

Varicella-Zoster virus (HHV-3)

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23
Q

Associated with Hodgkin’s lymphoma

A

EBV (HHV-4)

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24
Q

Transmission of Parvovirus B19

A

respiratory droplets

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25
Common warts
HPV 2 and 4
26
Diseases caused by HHV-7
Clinically insignificant
27
Polyoma virus that infects man and monkey
SV40
28
Complication of zoster
Postherpetic neuralgia (pain after rash heals which persists for up to months/years)
29
Epidermodysplasia verruciformis
HPV 5 and 8
30
This virus lyses the oligodendroglia causing destruction of cerebral white matter in patchy distribution
JCV (polyoma virus)
31
Complications of this infection include bacterial superinfection of skin, lungs, or bones by S. aureus or Group A strep.
Varicella (HHV-3)
32
Causes smallpox
Variolavirus
33
HBV nucleocapsid antigen
c Antigen
34
Associated with Burkitt's lymphoma
EBV (HHV-4)
35
Causes Roseola infantum (exanthem subitum)
HHV-6
36
DNA virus that causes mononucleosis
EBV (HHV-4) CMV (HHV-5) causes a mononucleosis-like illness
37
DNA virus that causes pruritic rash of red papules --> vesicles on stomach, back, face (scalp to trunk to extremities)
VZV (HHV-3)
38
Causes Kissing Disease
EBV (HHV-4) aka infectious mononucleosis
39
Causes watery conjunctivitis
Adenovirus
40
Causes oral lesions, along with spontaneous temporal lobe encephalitis, keratoconjunctivitis
HSV-1
41
"milkmaid's blisters" | Cowpox
Vacciniairus | used in vaccine that eradicated smallpox
42
High-grade fever --> resolves --> appearance of maculopapular rash
Roseola infantum (HHV-6)
43
Transmission of VZV
Varicella is airborne
44
HBV antigen providing protection
s Antigen
45
Associated with nasopharyngeal cancer
EBV (HHV-4)
46
Infection involves localized unilateral vesicular skin eruptions along 1-3 dermatomes
Zoster (shingles)
47
Fever, lymphadenopathy, exudative pharyngitis, atypical lymphocytosis are clinical manifestations
EBV (HHV-4)
48
Causes aplastic crisis in G6PD-D, sickle cell, thalassemia
Parvovirus B19
49
Associated with cervical and anogenital cancers
HPV 16 and 18
50
macular, papular, vesicular, pustular rashes --> crusts
Smallpox
51
Treatment of smallpox
methisazone, convalescent smallpox serum, vaccinia immuneglobulin
52
Treatment of CMV
ganciclovir
53
Treatment of EBV
supportive, short-course corticosteroids with inflammation
54
Treatment for HBV
Interferon, lamivudine
55
Treatment of polyomavirus
no specific treatment
56
Treatment of parvovirus B19
supportive, analgesic
57
Treatment of HPV
excision
58
Treatment of adenovirus
ribavarin and cidofovir (usually in immunocompromised)
59
Treatment of Herpes simplex
acyclovir | supportive
60
Treatment of Varicella
IV acyclovir
61
Cowdry A inclusions
HSV
62
B cell latent
EBV