Oncogenic viruses

Question 1

***What virus uses CD4, CXCR4, CCR5?

Answer 1

HIV

Question 2

What virus uses CD21 (complement receptor 2)

Answer 2

EBV

Question 3

***What virus uses CD46 and SLAM

Answer 3

Measles

Question 4

***What virus uses acetylcholine receptor

Answer 4

Rabies (think neurons)

Question 5

What virus uses Sialic acid-containing oligosaccharides

Answer 5

Reovirus

Question 6

What virus uses carcinoembryonic antigen gp family, aminopeptidase N, ACE 2

Answer 6

Coronavirus

Question 7

What virus uses CD55, CAR, integrins alpha, beta

Answer 7

Coxsackie virus

Question 8

What virus uses heparan sulfate; EGF receptor

Answer 8

CMV

Question 9

What virus uses GLUT-1

Answer 9

HTLV

Question 10

***What virus uses erythrocyte P antigen; and transferring receptor(canine)

Answer 10

parvovirus

Question 11

Hodgkin’s lymphoma in children

Answer 11

EBV

Question 12

Viruses whose genome can’t be used as mRNA

Answer 12

negative sense RNA viruses must transcribe into a positive sense using RNA polymerase

Question 13

Positive sense RNA viruses transcribe to DNA and incorporate into host genome

Answer 13

retroviruses

Question 14

RNA viruses replicate in cytoplasm except

Answer 14

influenza

retrovirus

Question 15

RNA viruses are ssrNA except

Answer 15

reovirus

Question 16

All DNA viruses can cause cancer except

Answer 16

parvo

Question 17

100% nasopharyngeal carcinoma

Answer 17

EBV

Question 18

HPV protein responsible for p53 tumor suppressor gene binding

Answer 18

E6

Question 19

HPV subtypes associated with cervical cancer

Answer 19

HPV 16, 18

Question 20

What HPV protein is responsible for the suppression of another protein responsible for tumor?

Answer 20

E2 suppresses E6 which suppresses P53 which suppresses tumor growth

Question 21

Members of polyoma family:

Answer 21

(PAPOVA)
PApilloma v
POlyoma v
VAcuola v

Question 22

Causes hemorrhagic cystitis in BM transplant Px

Answer 22

BK (think Bad Kidney)

Question 23

HPV subtypes associated wtih oropharyngeal cancer

Answer 23

HPV 16

Question 24

Causes progressive multifocal leukoencephalopathy

Answer 24

JC (think Junky Cerebrum

Question 25

Theses viruses can induce tumors in mice and hamsters after injection. Affect kidneys or brain in humans.

Answer 25

JC and BK (Polyoma)

Question 26

Receptor for HHV-8

Answer 26

Integrin alpha3beta1

Question 27

HPV subtypes associated with laryngeal papilloma in children

Answer 27

HPV 6, 11

Question 28

Burkitt's lymphoma

Answer 28

EBV

Question 29

All DNA viruses replicate in nucleus except

Answer 29

Poxvirus

Question 30

Virus associated with anogenital cancer

Answer 30

HPV

Question 31

Cervical intraepithelial neoplasia -- what virus?

Answer 31

HPV

Question 32

Dysregulation of this gene leads to Burkitt's

Answer 32

c-myc

Question 33

Causes Kaposi's sarcoma

Answer 33

HHV-8

Question 34

Hepatitis viruses with hepatocellular carcinoma risk

Answer 34

HBV (oncogene) | HCV (from chronic inflammation)

Question 35

HBV is of this family?

Answer 35

DNA - Hepadnavirus

Question 36

HCV is of this family?

Answer 36

RNA - flavivirus

Question 37

HBV marker for immunity from infection

Answer 37

Anti-HBsAg

Question 38

HBV marker IgM anti-HB indicates

Answer 38

acute Hep B

Question 39

Marker for HBV that indicates immunity through vaccination

Answer 39

HBsAg S antigen could also indicated acute/chronic hep b infection

Question 40

Serological tests revealed: (+) HBsAg (+) anti-HBeAg

Answer 40

Chronic HBV - high infectivity positive s antigen positive e antibody

Question 41

Serological tests revealed: (+) HBsAg (+) HBeAg

Answer 41

Acute HBV positive s and e antigen

Question 42

Serological tests revealed: | (+) Anti-HBsAg only

Answer 42

immunization to HBV

Question 43

Serological tests revealed: (+) Anti-HBsAg (+) Anti-HBeAg IgG Anti-HBcAb

Answer 43

HBV immunity from infection

Question 44

Serological tests revealed: | Antibody to HBcAg is IgM type

Answer 44

Acute HBV IgG antibody indicates chronic HBV

Question 45

Adult T cell leukemia/lymphoma

Answer 45

HTLV-1

Question 46

Malignancies associated with HIV

Answer 46

Kaposi's sarcoma Non-Hodgkin's B cell lymphoma Rectum and tongue CA

Question 47

Avian retrovirus

Answer 47

alpha

Question 48

mouse retrovirus

Answer 48

beta

Question 49

gamma retrovirus

Answer 49

mammals

Question 50

delta retrovirus

Answer 50

Human T-lymphotropic virus

Question 51

fish retrovirus

Answer 51

epsilon

Question 52

lentivirus

Answer 52

HIV