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Microbiology > RNA Viruses > Flashcards

RNA Viruses Flashcards

1
Q

Single-stranded, positive sense, ENVELOPED, icosahedral RNA virus

A 
Flavivirus:
HCV
HGV
West nile
Dengue
Yellow fever

Togavirus:
Rubella

Retrovirus:
HTV
HTLV
Sarcoma

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2
Q

Single-stranded, positive sense, ENVELOPED, helical RNA virus

A

Corona virus

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3
Q

Single-stranded, positive sense, NAKED, icosahedral RNA virus

A

Calici:
Norwalk/Noro
Sapovirus
HEV

Picorna:
Polio
Entero
Echo
Coxackie
Rhino
HAV

Astrovirus

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4
Q

Single-stranded, negative sense, enveloped, HELICAL, RNA virus

A 
Paramyxo:
Mumps
Measles
RSV
Parainfluenza

Filo:
Marburg
Ebola

Orthomyxo:
Influenza

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5
Q

Single-stranded, negative sense, enveloped, BULLET, RNA virus

A

Rhabdo:
Rabies
Vesicular stomatitis

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6
Q

Single-stranded, ambisence and negative sense, enveloped, helical RNA virus

A

Arena:
LCV
Lassa fever

Bunya:
Hantavirus
CCHF
Cali encephalitis

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7
Q

All RNA virus have single-stranded DNA except?

A

Reovirus

Rotavirus

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8
Q

All RNA viruses replicate in the cytoplasm except?

A

Influenza

Retrovirus

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9
Q

MC clinical form of poliomyelitis

A

Abortive poliomyelitis

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10
Q

Cowdry type B intranuclear inclusions

A

Poliovirus

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11
Q

Killed polio vaccine

A

Salk IPV (injection)

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12
Q

Live, attenuated polio vaccine

A

Sabin OPV (oral)

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13
Q

MCC of myocarditis and pericarditis

A

Coxsackie virus

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14
Q

MCC of aseptic meningitis

A

Enteroviruses:
Coxsackie
Polio
Echo

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15
Q

Causes hand, foot, and mouth disease

A

Coxsackie virus

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16
Q

Enteric cytopathic human orphan

A

Echovirus

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17
Q

MCC of common colds

A

Rhinovirus

2nd: Coronavirus

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18
Q

Most frequently infected by Hepa A

A

Children

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19
Q

Most impt test for Hepa A

A

Anti-HAV IgM

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20
Q

Hepa E has high mortality in?

A

Pregnant women

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21
Q

MCC of nonbacterial diarrhea in adults

A

Norwalk/Norovirus

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22
Q

MCC of childhood diarrhea

A

Rotavirus

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23
Q

Type of influenza which causes pandemic

A

Influenza A

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24
Q

Type of influenza which causes major outbreaks of influenza (does not lead to pandemic)

A

Influenza B (only a human virus)

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25
Virulence factor of Influenza virus for binding; it is the target of neutralizing antibody
Hemagglutinin
26
Virulence factor of Influenza virus for entry; cleaves neuraminic acid (sialic acid)
Neuraminidase
27
Causes influenza pandemic
Antigenic shift | Influenza A
28
Causes influenza epidemics
Antigenic drifts (Influenza B)
29
Complications of Influenza virus
Staph pneumonia | Reye syndrome
30
DOC for influenza virus
Oseltamivir or Zanamivir
31
Drug for influenza A only
Amantadine or rimantadine (prevents viral uncoating)
32
Symptom unique to influenza
Myalgia
33
Damson disease is also called as?
Subacute sclerosing panencephalitis (Measles)
34
Associated with type 1 DM
Mumps virus
35
Warthin finkeldey giant cells
Measles
36
Most important cause of pneumonia and bronchiolitis in infants
RSV
37
DOC for RSV infection (viral pneumonia)
Ribavirin
38
Steeple sign
Croup (Laryngotracheobronchitis)
39
Causes croup
Parainfluenza virus 1 and 2
40
DOC for croup
Racemic epinephrine
41
Negri bodies
Rabies
42
Club-shaped spikes
Coronavirus
43
CXR: noncavitary "ground-glass" infiltrates
SARS (coronavirus)
44
Atypical pneumonia rapidly progressing to ARDS
SARS
45
Most specific test for dengue
Dengue PCR
46
Laterality of pleural effusion in dengue
Right
47
Criteria for severe dengue
Severe plasma leakage Severe bleeding Severe organ involvement
48
Warning signs of dengue
``` Abdominal pain/tenderness Persistent vomiting Clinical fluid accumulation Mucosal bleed Lethargy, restlessness Liver enlargement >2cm Increase in HCT concurrent with rapid decrease in platelet count ```
49
Most prevalent blood-borne pathogen
Hepa C (IV drug abusers)
50
It greatly enhances rate of hepa ca caused by Hepa C
Alcoholism
51
Hepa infection with autoimmune reactions (thyroiditis, etc)
Hepa C
52
Main cause of essential mixed cryoglobulinemia
Hepa C
53
MCC indication for liver transplantation
Cirrhosis caused by Hepa C
54
DOC for acute hepa C in children
Interferon
55
DOC for chronic hepa C
Peginterferon | Ribavirin
56
Prodrome followed by 3-day maculopapular rash and postauricular LAD
Rubella
57
5 Bs of congenital rubella syndrome
``` Bulag- cataracts Bingi- sensorineural deafness Bobo- MR Butas ang puso (PDA) Blueberry muffin baby ```
58
RNA dependent DNA polymerase
Reverse transcriptase (Retrovirdae)
59
HIV fusion protein
GP41
60
HIV attachment protein
GP120
61
HIV major capsid protein; impt for dx
p24
62
HIV: directs entry of the dsDNA provirus into the nucleus
MA (p17)
63
HIV: responsible for rapid antigenic changes
gp120
64
Gene responsible for activation of transcription of HIV viral genes
Tat gene
65
#1 cause of mortality in AIDS
Disseminated TB
66
PCP pneumonia in AIDS occurs when CD4 count is?
67
TB, esophageal candidiasis, and kaposi sarcoma in AIDS occurs when CD4 count is?
68
MC AIDS-defining illness
P. carinii pneumonia
69
Used to monitor response and for prognostication in AIDS
PCR
70
Highly active antiretroviral therapy (HAART)
2 nucleoside inhibitors (zidovudine + lamivudine) + protease inhibitor (indinavir)
71
Malignant T cells with flower-shaped nucleus
Adult T cell leukemia | HTLV-associated myelopathy
72
Thread-like viruses; longest viruses
Ebola virus (filoviridae)
73
Virus with bird-mosquito-man cycle
West nile virus
74
MCC of epidemic encephalitis
Japanese B encephalitis
75
Area in the brain affected by Japanese B encephalitis
Thalamus (thalamic infarcts)
76
Double-stranded, naked, icosahedral, linear, RNA virus
Reovirus: Rotavirus Colorado Tick fever

Microbiology (9 decks)

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