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Other Bacteria Flashcards

1
Q

Ulceroglandular disease at the site of bite

A

Francisella tularensis

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2
Q

Most virulent bacteria; bipolar (safety pin) staining; buboes

A

Y. pestis

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3
Q

DOC for Y. pestis

A

Streptomycin and Tetracycline

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4
Q

Ziehl-neelsen stain

A

M. tuberculosis

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5
Q

Virulence factor of M. tuberculosis which prevents phagosome-lysosomal fusion

A

Exported repetitive protein (Sulfatides)

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6
Q

Most impt virulence factor of M. tuberculosis which prevents leukocyte migration

A

Cord factor

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7
Q

Virulence factor of M. tuberculosis which elicits delayed type hypersensitivity

A

Tuberculin surface protein

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8
Q

Central area of Langhan’s giant cells surrounded by a zone of epithelioid cells

A

Granuloma

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9
Q

A granuloma surrounded by fibrous tissue that has undergone central casseation

A

Tubercle

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10
Q

Subpleural granuloma is also called as?

A

Ghon’s focus

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11
Q

Ghon’s focus + associated lymph node

A

Ghon’s complex

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12
Q

Radiologically detectatable calcification in TB

A

Ranke’s complex

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13
Q

Reactivation TB in apices

A

Simon’s focus

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14
Q

CXR: cicatricial changes, subpleural blebs, cavitation, fibrosis, nodules

A

Reactivation TB

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15
Q

Fungi associated with reactivation TB

A

A. fumigatus

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16
Q

MC extrapulmonary form of TB

A

Scrofula/TB adenitis

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17
Q

Causes Hansen disease; red snappers

A

M. leprae

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18
Q

Positive lepromin skin test

A

Tuberculoid leprosy

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19
Q

Paucibacillary leprosy; few lesions; + cell-mediated response

A

Tuberculoid leprosy

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20
Q

Hypopigmented plaques, thickened superficial nerves, and significant anesthesia

A

Tuberculoid leprosy

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21
Q

Leonine facies; erythema nodosum leprosum

A

Lepromatous leprosy

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22
Q

Tender red nodules or humps on both shins seen in leprosy; signals acute flare-ups

A

Erythema nodosum leprosum

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23
Q

DOC for tuberculoid leprosy

A

Dapsone

Rifampin

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24
Q

DOC for lepromatous leprosy

A

Dapsone
Rifampin
Clofazimine

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25
DOC for erythema nodosum leprosum
Thalidomide
26
Thalidomide is associated with what congenital malformation?
Phocomelia
27
Hard, nontender swelling with sinus tracts draining sulfur granules
Actinomycosis (Actinomyces israelii)
28
DOC for Actinomycosis
Penicillin G + drainage
29
Manifests as mycetomas and lung and brain abscesses (orange colonies)
Nocardiosis (Nocardia asteroides)
30
Smallest free-living organisms; only bacteria with cholesterol in cell membrane
Mycoplasma pneumoniae
31
Virulence factor of Mycoplasma pneumoniae used for attachment, inhibition of ciliary motion, and necrosis
Toll-like receptor 2 protein (P1 adhesin)
32
MC type of atypical pneumonia (walking pneumonia)
Mycoplasma pneumoniae
33
MC infectious cause of SJS
Mycoplasma pneumoniae
34
DOC for Mycoplasma pneumoniae infection
Erythromycin or azithromycin
35
Coiled spirochete; too thin; microaerophilic; cannot be cultured in vitro
Treponema pallidum
36
Chancre: What stage of syphilis infection?
Primary syphilis
37
Condyloma acuminata, maculopapular rash, lymphadenopathy: What stage of syphilis infection?
Secondary syphilis
38
Granulomas (gummas), neurosyphilis; What stage of syphilis infection?
Tertiary syphilis
39
Argyll-Robertson pupil; Prostitute's pupil
Tabes dorsalis
40
Snuffles/saddles nose, mulberry molars, Hutchinson triad, saber shins, Higoumenaki sign, clutton joints, pulmonary hemorrhage
Congenital syphilis
41
Hutchinson triad
HuDeKer Hutchinson teeth Deafness Keratitis
42
Most impt dx test for primary syphilis
Dark-field microscopy
43
Screening test for secondary/tertiary syphilis
RPR/VDRL
44
Confirmatory test for secondary/tertiary syphilis; earliest positive; remains positive the longest
FTA-ABS
45
DOC for syphilis
Benzathine penicillin G
46
Influenza-like sx few hours after receiving penicillin due to lysis of treponemes
Jarisch-Herxheimer rxn
47
Largest medically-impt bacteria
Borrelia burgdorferi
48
Stage 1 of Lyme disease
Erythema chronicum migrans (target lesion)
49
Stage 2 Lyme disease
Myocarditis (AV block), meningitis, Bell's palsy
50
Stage 3 Lyme disease
Autoimmune migratory polyarthritis (onion skin lesions), acrodermatitis chronica atrophicans
51
DOC for lyme disease
Doxycycline
52
Causes relapsing fever
Borrelia recurentis
53
Borrelia recurentis is transmitted by what insect?
Pediculus humanus
54
DOC for relapsing fever
Tetracycline or Erythromycin
55
Thin, coiled spirochete with shepherd's crook (hook at one or both pointed ends); obligate aerobe
L. interrogans
56
Best specimen for early stages of leptospirosis infection
Blood and CSF | Urine for later stages
57
Gold standard dx test for leptospirosis
Lepto MAT
58
CXR: snow-flake lesions
Leptospirosis
59
Triad of Weil syndrome
Jaundice Uremia Bleeding
60
MCC of death in leptospirosis
Respiratory failure due to massive pulmonary hemorrhage
61
DOC for mild leptospirosis
Doxycycline Amoxicillin Ampicillin
62
DOC for severe leptospirosis
Pen G | Ampicillin
63
Obligate intracellular bacteria; energy parasites that use host ATP; cell wall lacks muramic acid
Chlamydia trachomatis
64
Culture medium for Chlamydia trachomatis
Cycloheximide
65
MC STD overall
Chlamydia trachomatis
66
Round to oval cytoplasmic inclusion bodies near the nuclei of conjunctival epithelial cells in trachoma
Halberstadter-Prowazel inclusions
67
Chlamydia trachomatis serotype which causes STDs
D-K | Assoc. with Reiter syndrome
68
Positive Frei test
Lymphogranuloma venereum
69
Associated with atherosclerosis
Chlamydia pneumoniae
70
Causes bird fancier's disease
Chlamydia psitacci
71
Positive Weil-Felix reaction
Rickettsiae
72
DOC for Rickettsial infection
Doxycycline
73
Palm and Sole Rash
Coxsackie virus type A Rocky mountain spotted fever Syphilis
74
Causes cat scratch disease in immunocompetent individuals
Bartonella henselae
75
Causes bacillary angiomatosis in immunocompromised individuals
Bartonella henselae
76
Transmitted by dog tick (Dermacentor)
Ehrlichia chaffeensis
77
Clue cells; positive whiff test (fishy odor)
Bacterial vaginosis (Gardnerella vaginalis)
78
Painful genital ulcer
H. ducreyi
79
Causes mesenteric adenitis (pseudoappendicitis)
Yersinia enterocolitica
80
Causes granuloma inguinale (Donovanosis)
Klebsiella granulomatis
81
Bipolar bodies (donovan bodies) look like closed safety pins; pseudobuboe
Klebsiella granulomatis
82
DOC for Klebsiella granulomatis
Azithromycin
83
Causes undulating fever; transmission is through contaminated dairy products or through direct contact
Brucella abortus

Microbiology (9 decks)

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