DNA Viruses Flashcards

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1
Q

All DNA virus have linear DNA except?

A

Papilloma
Polyoma
HepaDNA

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2
Q

All DNA virus are icosahedral except?

A

Poxvirus

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3
Q

All DNA virus replicate in the nucleus except?

A

Poxvirus

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4
Q

Naked DNA viruses

A

Parvovirus B19
Adenovirus
Human papillomavirus

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5
Q

The only naked DNA virus which is oncogenic

A

HPV

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6
Q

Associated with hydrops fetalis

A

Parvovirus B19

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7
Q

Fifth disease is caused by?

A

Parvovirus B19

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8
Q

The only virus with fiber (penton fiber)

A

Adenovirus

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9
Q

Cowdry type B intranuclear inclusions

A

Adenovirus

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10
Q

Viral cause of hemorrhagic cystitis

A

Adenovirus

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11
Q

Virus which causes skin and plantar warts

A

HPV 1-4

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12
Q

Virus which causes genital warts (condyloma acuminata) and respiratory tract papillomas

A

HPV 6 and 11

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13
Q

Virus which causes ca of the cervix, penis, and anus

A

HPV 16, 18, 31, 33

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14
Q

Causes progressive multifocal leukoencephalopathy in patients with AIDS

A

JC polyoma virus

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15
Q

Enveloped DNA virus

A
HSV-1
HSV-2
VZV
EBV
CMV
HHV-8
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16
Q

Herpesviruses

A

CMV
HSV
EBV
VZV

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17
Q

HSV lesions above the umbilicus

A

HSV-1

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18
Q

HSV lesions below the umbilicus

A

HSV-2

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19
Q

Site of latency for HSV-1

A

Trigeminal ganglia

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20
Q

Site of latency for HSV-2

A

Lumbosacral ganglia

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21
Q

Large, pink to purple intranuclear inclusions (Cowdry type A)

A

HSV

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22
Q

Multinucleated giant cells seen on Tzanck smear

A

HSV

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23
Q

Causes temporal lobe encephalitis

A

HSV

24
Q

DOC for HSV

A

Acyclovir

25
Q

Dewdrop on a rose petal appearance; vesicular centrifugal rash

A

Varicella

26
Q

Uses of aspirin in pediatric diseases

A

Kawasaki disease
ARF
JRA

27
Q

Involvement of geniculate ganglion by Varicella causes facial nerve paralysis

A

Ramsay Hunt Syndrome

28
Q

Negative heterophil test

A

CMV

29
Q

Positive heterophil test

A

EBV

30
Q

Giant cells with owl’s eye nuclear inclusions

A

CMV

31
Q

MCC of congenital abnormalities

A

CMV

32
Q

DOC for CMV infection

A

Gamciclovir

33
Q

MCC of blindness in HIV patients

A

CMV retinitis

34
Q

DOC for CMV retinitis

A

Foscarnet

35
Q

Etiologic agent of Kissing disease

A

EBV

36
Q

Ca associated with EBV

A

Burkitt lymphoma
B cell lymphoma
Nasopharyngeal ca
Hairy leukoplakia in AIDS patients

37
Q

Causes Kaposi’s sarcoma

A

Human Herpesvirus-8

38
Q

Largest virus

A

Variola (smallpox)

39
Q

Brick-shaped poxvirus containing linear dsDNA

A

Variola (smallpox)

40
Q

Intracytoplasmic eosinophilic inclusions seen in smallpox

A

Guarnieri bodies

41
Q

Pinkish, papular skin lesions with an umbilicated center

A

Molluscum contagiosum

42
Q

Intracytoplasmic eosinophilic inclusions seen in Molluscum contagiosum

A

Henderson-Peterson bodies

43
Q

DOC for Molluscum contagiosum

A

Cidofovir

44
Q

Enveloped virus with incomplete circular dsDNA

A

Hepa B virus

45
Q

Only DNA virus that produces DNA by reverse transcription with mRNA as the template

A

Hepa B virus

46
Q

Autoimmune vasculitides associated with Hepa B

A

Polyarteritis nodosa

47
Q

Complications of Hepa B infection

A

Hepatorenal syndrome

Hepatopulmonary syndrome

48
Q

1st vaccine to prevent human ca

A

Hepa B vaccine

49
Q

DOC for Hepa B infection

A

Interferon alpha

Lamivudine

50
Q

HBsAg: +
Anti-HBs: -
Anti-HBc: -
HBeAg: +

A

Incubation period

51
Q

HBsAg: +
Anti-HBs: -
Anti-HBc: + IgM
HBeAg: +

A

Acute infection

52
Q

HBsAg: -
Anti-HBs: -
Anti-HBc: + IgM
HBeAg: -

A

Window period

53
Q

HBsAg: -
Anti-HBs: +
Anti-HBc: + IgG
HBeAg: -

A

Complete recovery

54
Q

HBsAg: +
Anti-HBs: -
Anti-HBc: + IgG
HBeAg: -

A

Chronic carrier

55
Q

HBsAg: +
Anti-HBs: -
Anti-HBc: +IgG
HBeAg: +

A

Chronic active

56
Q

HBsAg: -
Anti-HBs: +
Anti-HBc: -
HBeAg: -

A

Vaccinated

57
Q

All DNA viruses have double-stranded DNA except?

A

Parvovirus