Risperidone Flashcards
what is Risperidone
Multitarget antipsychotic, an atypical antipsychotic therapy
What is Risperidone
used to treat delusional psychosis, bipolar disorder and psychotic depression
how does Risperidone
Its mechanism of action is inhibition of
1) Dopaminergic D2 receptors in the limbic system which alleviates symptoms of schizophrenia.
2) Serotonergic 5-HT2 receptors in the mesocortical tract. This causes an excess of dopamine and an increase in dopamine transmission and an elimination of core negative symptoms. Usefully dopamine receptors in the nigrostriatal pathway are not affected and therefore extrapyramidal effects are avoided.
3) Alpha (1), alpha (2) adrenergic receptors and histamine H1 receptors