Rheumatology Short Flashcards

1
Q

Pattern of joint involvement in RA?

A

symmetrical deforming small joint polyarthritis sparing DIPs

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2
Q

Extra articular signs of psoriatic arthritis?

A
psoriatic rash
dactylitis
enthesitis 
nail pitting, ridging, onycholysis
aortic regurgitation 
apical lung fibrosis
conjunctivitis/uveitis
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3
Q

Risk factors for destructive disease in RA?

A
high titre RF or positive anti CCP
constitutional symptoms
erosions early on XR
rheumatoid nodules early
HLA-DR4
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4
Q

Causes of early onset osteoarthritis?

A
trauma
juvenile arthritis
haemochromatosis
acromegaly
charcot's joint
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5
Q

Antibodies associated with SLE?

A

anti dsDNA
anti-Sm
ANA

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6
Q

Antibodies associated with systemic sclerosis?

A

Anti-Scl-70

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7
Q

Antibodies associated with limited sclerosis?

A

anti-centromere

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8
Q

Antibodies associated with scleroderma renal crisis?

A

anti-RNA polymerase III

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9
Q

Extra articular manifestations of ankylosing spondylitis (6 As)?

A
apical lung fibrosis
AR
anterior uveitis
achilles tendonitis (enthesitis)
atlanto-axial subluxation 
amyloidosis
(+ IBD)
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10
Q

What joint deformities may be present in RA?

A
swan neck deformity
boutonniere deformity
ulnar deviation of MCP
radial deviation of wrist joint
z deformity of thumb
volar (anteior) subluxation of the fingers - towards palm
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11
Q

Findings on hand examination in scleroderma?

A
sclerodactyly
calcinosis
raynaud's
digital ulceration
telangectasia
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12
Q

Extra articular manifestations of RA?

A
eye disease - episcleritis/scleritis
anaemia
ILD
pleural effusions
pericardial effusions
pyoderma gangrenosum
splenomegaly
mononeuritis multiplex
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13
Q

What are the possible causes of anaemia in a patient with RA?

A
anaemia of chronic disease
GI blood loss due to NSAIDs
folate deficiency due to methotrexate
pernicious anaemia
bone marrow suppression due to methotrexate
felty's syndrome
autoimmune haemolytic anaemia
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14
Q

What are the 5 different patterns of joint involvement in psoriatic arthritis?

A

assymmetrical oligoarthritis involving mainly DIPs
symmetrical polyarthritis sparing DIPs (RA pattern)
DIP arthritis
arthritis mutilans
spondyloarthritis

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15
Q

Which biologics are used for the management of psoriatic arthritis?

A

anti-TNF
anti-IL17
anti-IL23/23
JAK inhibitor

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16
Q

Additional examination findings beyond the hands to look for in scleroderma?

A

interstitial lung disease
pulmonary hypertension
hypertension
proteinuria

17
Q

Clinical findings for dermatomyositis?

A

heliotrope rash
gottron’s papules
poikiloderma
proximal myopathy

18
Q

Clinical findings for SLE?

A
butterfly rash
alopecia
raynaud's
symmetric non erosive polyarthritis
mouth ulcers
ILD
pleural effusions
pericarditis
pulmonary HTN
mononeuritis multiplex
proteinuria/haematuria
lymphadenopathy
splenomegaly