Renal Short Flashcards

1
Q

Side effects of CN inhibitors?

A
hypertension
nephrotoxicity
gum hypertrophy
seizures
alopecia
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2
Q

Side effects of mycophenolate?

A

leukopenia

GI upset

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3
Q

Side effects of sirolimus/everolimus?

A
proteinuria
hyperlipidaemia
leukopaenia
pneumonitis
tendon rupture
slow wound healing
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4
Q

Common causes of CKD?

A

diabetes
GN
HTN
ADPKD

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5
Q

Associations with IgA nephropathy?

A

HIV
chronic liver disease
IBD
coeliac disease

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6
Q

Secondary causes of membranous nephropathy?

A
malignancy
Hep B/C/HIV
drugs
thyroiditis
sarcoidosis
post renal transplant
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7
Q

Extra renal manifestations of ADPKD?

A
liver cysts
pancreatic cysts
splenic cysts
thyroid cysts
seminal vesicle cysts
intracranial cerebral aneurysms
diverticular disease
hernias
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8
Q

Complications of CKD?

A
anaemia
bone disease
HTN
infection
acidosis
hyperkalaemia 
fluid overload 
CV disease
uraemia
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9
Q

Causes of delayed graft function?

A
post ischaemic ATN
graft thrombosis
obstruction/urine leak
hyper acute rejection
early disease recurrence
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10
Q

Causes of early worsening graft function?

A
graft thrombosis
acute rejection
CNI toxicity
renal artery stenosis
obstruction/leak
BK nephropathy
CMV
recurrent disease
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11
Q

Causes of bilateral renal masses?

A
polycystic kidneys
hydronephrosis
bilateral renal cell carcinoma
bilateral acute renal vein thrombosis
amyloidosis
acromegaly
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12
Q

Causes of unilateral renal masses?

A

renal cell carcinoma
hydronephrosis
polycystic kidneys
aute renal vein thrombosis

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13
Q

What are the indications for nephrectomy in ADPKD?

A
recurrent infections
chronic pain
recurrent haematuria
early satiety
pre transplantation
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14
Q

Differential diagnosis for renal cysts?

A
benign renal cysts
renal cell carcinoma
polycystic kidney disease
amyloidosis
von hippel lindau syndrome
tuberous sclerosis
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15
Q

Investigations for worsening graft function?

A
CRP
CMV serology
BK virus PCR
immunosuppression drug levels
urinalysis
US
biopsy
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16
Q

What is the definition of nephrotic syndrome?

A
proteinuria > 3.5g/24 hours
hypoalbuminaemia < 30
oedema
hyperlipidaemia
coagulopathy
17
Q

Differential diagnosis for nephrotic syndrome?

A
membranous nephropathy (33%)
FSGS (35%)
minimal change disease (15%)
amyloidosis (4%)