Rheumatology Flashcards

1
Q

What is pannus?

A

synovial membrane-derived granulation tissue that overgrows and destroys joint cartilage

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2
Q

What type of exercises should be used for acutely inflammed joints?

A

isometric

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3
Q

Deformity of hand and wrist seen in RA?

A

radial deviation of the wrist, ulnar deviation of the fingers

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4
Q

What type of arthritis is seen in lupus?

A

non-erosive

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5
Q

Two drugs used in prevention of gout that decrease uric acid production?

A

allopurinol and febuxostat

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6
Q

first choice treatment for acute gout attack?

A

indomethacin

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7
Q

most common cause of septic arthrits in children?

A

staph aureus

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8
Q

most common cause of septic arthritis in adults?

A

neisseria gonorrhea

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9
Q

What causes ocular inflammation in an RF+ patient?

A

Sjogrn Syndrome

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10
Q

synovial fluid WBC count in RA?

A

1,000 - 75,000

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11
Q

What percent of RA patients are RF (+)?

A

75%

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12
Q

What disease can be confused with early RA?

A

de Quervain’s tenosynovitis

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13
Q

What size A-A space is considered abnormal?

A

> 2.5 mm

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14
Q

What is the most common type of A-A joint subluxation?

A

anterior

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15
Q

Besides RA, what other disease presents with subcutaneous nodules?

A

Gout

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16
Q

What can cause chest pain in RA patients?

A

Pericarditis

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17
Q

What presents with RA, leukopenia, and an enlarged spleen?

A

Felty’s Syndrome

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18
Q

What ligament is involved with diffuse idiopathic skeletal hyperostosis (DISH)?

A

ALL

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19
Q

Are erosive changes seen on x-ray in osteoarthritis?

A

No, but they are in RA.

20
Q

most common joint involved in oligoarticular juvenile idiopathic arthritis?

A

knee

21
Q

referral to what specialty is mandatory with diagnosis of oligoarticular JIA?

A

Ophthalmology for evaluation of iridocyclitis

22
Q

labs normally positive in oligoarticular JIA?

A

ANA, HLA-B27

23
Q

Joint most commonly involved with pseudogout?

A

knee

24
Q

With pseudogout, what types of labs should be ordered due to association with other diseases?

A
  • thyroid (hypothyroid, hyperparathyroid)
  • iron (hemochromatosis)
  • Mg (hypomagnesmia)
  • Phosphate (hypophosphatemia)
25
Q

What types of diuretics can provoke gout?

A

thiazides, loop

26
Q

Three treatments that can be used for acute gout or pseudogout?

A

NSAIDs, Corticosteroids, Colchicine

27
Q

What develops in 75% of patients who have long-term ankylosing spondylitis ( >16 years)?

A

cervical ankylosis

28
Q

What causes the finding of “bamboo spine” in ankylosis spondylitis?

A

ossification of the annulus fibrosis with bridging syndesmophytes

29
Q

Test used to detect limitation of forward flexion in ankylosis spondylitis?

A

Schober’s ( < 5mm increase in distance with flexion is positive)

30
Q

How should someone with ankylosis spondylitis sleep?

A

prone on a firm matteress

31
Q

What is the triad of reactive arthritis?

A

conjunctivitis, nongonoccal urethritis, arthritis

32
Q

Up to 10% of reactive arthritis patients can progress to what disease entity?

A

ankylosis spondylitis

33
Q

X-ray findng in reactive arthritis?

A

erosion at insertion of achilles tendon and plantar fascia

34
Q

Joints affected by enteropathic arthropathy?

A

knees, ankles, feet

35
Q

disease associated with psoriatic arthritis

A

HIV

36
Q

pharmacologic treatment for Raynaud’s phenomenon?

A

calcium channel blockers (nifedipine)

37
Q

What is type III dermatomyositis/polymyositis associated with?

A

malignancy

38
Q

What type of dermatomyositis/polymyositis is associated with children and severe joint contractures?

A

IV

39
Q

Up to 16% of patient’s with polymyalgia rheumatica go on to develop what serious condition?

A

temporal arteritis

40
Q

most common cause of septic arthritis in children 6 months to 2 years old?

A

Haemophilus influenza

41
Q

cause of diabetes, cirrhosis, and progressive arthritis in the hands?

A

hemochromatosis

42
Q

cause of arthritis in hemophilia?

A

hemosiderin from remaining blood deposits in the synovial lining and causes pannus formation

43
Q

Cause of charcot joint of the shoulder?

A

syringomyelia

44
Q

most common cause of hip pain in children?

A

acute transient synovitis

45
Q

what is Dupytren’s contracture?

A

fibrous hyperplasia of the palmar fascia causing contracture of MCP and PIP joints