Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

IM > Rheumatology > Flashcards

Rheumatology Flashcards

1
Q

What are the causes of acute Inflammatory mono articular arthritis?

A

Septic arthritis
Gout
Viral arthritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the causes of chronic Inflammatory mono articular arthritis?

A

Psoriatic arthritis
Sarcoidosis
Pseudogout

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the causes of acute nonInflammatory mono articular arthritis?

A

Mechanical stuff, trauma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the causes of acute Inflammatory peri articular arthritis?

A

Bursitis, tendinitis, septic bursitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the causes of acute Inflammatory polyarticular arthritis?

A

Viral (parvovirus), septic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the causes of chronic Inflammatory polyarticular arthritis?

A

RA, psoriatic, Lyme, scleroderma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How do you distinguish inflammatory vs noninflammatory joint swelling?

A

Inflammatory - morning stiffness. In the case of RA, lasts awhile

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Describe common location of psoriatic arthritis swelling

A

DIP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Decribe acute rheumatic fever

A

Occurs after event strep, migratory in nature, accompanied by carditis, chores, subcutaneous nodules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

describe symptoms associated with a spondyloarthropathy

A

Arthritis, tendinitis,uveitis, spinitis, enthesitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the presentation of RA?

A

small joints sparing the DIP - joints are swollen and tender to motion
morning stiffness for more than 1 hour

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How is RA diagnosed?

A

positive anti-CCP antibodies

high IgM rheumatoid factor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are some of the long term sequellae of RA?

A

anemia, fatigue, osteoporosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the side effects of methotrexate?

A

macrocytic anemia, nausea, stomatitis, rash, hepatotoxicity, interstitial lung disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the presentation of whipple disease?

A

malabsorptive diarrhea, migratory polyarthropathy, protein losing enteropathy, lymphadenopathy,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the cause of whipple disease?

A

tropheryma whipellii

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

How is whipple disease diagnosed?

A

ant-PAS positive macrophages with non acid fast bacilli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is the presentation of reactive arthritis?

A

arthropathy, conjunctivitis, urethritis following infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

A patient presents with enthesitis, shoulder and hip pain, and stiffness. This is likely…

A

anklyosing spondylitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is Still’s disease?

A

autoimmune disease characterized by fevers, salmon colored rash, juvenile idiopathic rash

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What are the diagnostic criteria of lupus?

A 
4 of the following 11:
serositis
oral ulcers
arthritis
photosensitivity
blood abnormalities
renal dysfunction
ANA positive
Immunologic testing (anti-SM, anti-dsDNA)
Neurologic - psychosis, seizures
Malar rash
Discoid rash - raised patches with scaling
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What tests should be run in considering an autoimmune disease?

A

C3/C4- low complement associated with flares
Antiphospholipid antibodies - associated with embolic disease
Anti - histone antibodies - associated with drug induced lupus
SSA/SSB - associated with Sjogrens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What are some other important manifestations of lupus?

A

fatigue, fever, weight loss, raynaud’s, hair loss, miscarriages, lymphadenopathy, marantic fevers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What treatments are available for RA?

A

start on DMARDs ASAP (methotrexate) - adjunctive therapy NSAIDS, hydroxychloroquine (good for skin flare,s joint disease), glucocorticoids, steroid sparing agents. if those don’t work, (tumor necrosis factor -alpha inhibitors)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

How is rotator cuff bursinitis differentiated from other rotator cuff pathology?

A

inject lido - if it works, it’s rotator cuff impingement

rotator cuff injury also associated with weakness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

How does vascular compression of the arm present?

A

numbness, weakness, swelling of the joint

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

What side effects are associted with hydroxychlroquine?

A

retinopathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

What side effects are associated with TNF inhibitors?

A

infection, demyelination, CHF, malignancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

A patient presents with joint pain worse in the morning for 60 minutes, worsened by activity, non tender, no systemic symptoms. This is likely

A

DJD

30
Q

A patient has recurrent lymphadema. This is likely due to

A

c1 esterase inhibitors

31
Q

A patient presents with widespread aching and stiffness in hips and shoulders, absence of tender points, inflammatory joints, ESR> 50. This is… (and how do you treat it?)

A

polymyalgia rheumatica - treat with low dose corticosteroids

32
Q

What antibodies are associated with RA?

A

CCA

33
Q

What does positive anti-centromeres indicate?

A

CREST syndrome (scleroderma)

34
Q

What does positive ANA - SCL-70 indicate?

A

scleroderma

35
Q

What does positive anti-smith antibody indicate?

A

lupus

36
Q

What does anti-Jo antibody indicate?

A

polymyositis

37
Q

What does anti- RNP antibody indicate?

A

mixed connective tissue disease

38
Q

What does anti-histone antibody indicate?

A

drug induced lupus

39
Q

What is the treatment of choice for acute gout?

A

NSAIDs, colchicine

40
Q

What is the prophylactic treatment for gout?

A

allopurinol

41
Q

What are the poor prognostic signs of RA?

A

positive anti-CCP antibodies and subcutaneous nodules

42
Q

A patient presents with migratory arthritis, pancarditis, erythema marginatum and subcutaneoous nodules. What titer would be elevated (And what is this?)

A

anti-streptolysin titers elevated - this is acute rheumatic fever

43
Q

A patient presents with arthralgias, palpable purpura, lymphadenopathy, nephropathy and neuropathy. What titers would be elevated and what disease does this patient likely have?

A

low C3, cryoglobulin levels elevated - this patient likely has hepatits C

44
Q

What are the classic findings of hemachromatosis at the joints?

A

squared off bone ends and hook like osteophytes

45
Q

What does CREST syndrome stand for?

A

calcinosis, raynaud’s, esophageal dysmotility, sclerodactyly, telangectasias (on the face and hands)

46
Q

A patient presents with hx of RA, enlarged kidneys and enlarged liver. What test should be performed next?

A

renal biopsy and staining with congo red to look for amyloid until red-green birefuringence

47
Q

Is the arthritis associated with SLE permament?

A

nope!

48
Q

A patient presents with a facial rash, difficulty rising from a seated position, a dusky malar rash and violaceous periorbital edema. What is this associated with?

A

this is dermatomyositis - associated with malignancy

49
Q

What autoantibody is associated with dermatomyositis?

A

anti-Mi-2 (against helicase)

50
Q

What are the cautions given when starting methotrexate?

A

don’t plan on getting pregnant, no drinking, no renal disease or liver disease; check for hep B and hep C

51
Q

A patient presents with fever, leukocytosis and redness and swelling of the knee and crystals aspirated show rhomboid shaped, positively birefringent. This will show up on X ray with

A

chondorcalcinosis - this is pseudogout

52
Q

A patient with gout is aspirated - what is the appearence of the crystals found?

A

needle shaped, negatively bifuringent crystals

53
Q

A patient presents with right sided neck pain and numbness over the posterior forearm. What is the most likely finding on radiograph?

A

bony spurs - this is cervical spondylosis

54
Q

A patient presents with joint pains, right heel pain, urethritis, conjunctivitis with sterile synovial fluid. What is tx?

A

NSAIDs for reactive arthritis

55
Q

A patient presents with headaches, sudden loss of vision, a swollen pale disc with blurred margins and elevated ESR. What is the next step of treatment?

A

This is giant cell arteritis (also known as temporal arteritis) - start on high dose steroids immediately to avoid vision loss

56
Q

A patient presents with chronic aching pain, stiffness in the neck and shoulders and has multiple tender spots all over her body. What is the appropriate treatment?

A

amitryptaline for fibromylagia rheumatica

57
Q

What is the most important intervention to prevent gout flares?

A

alcohol cessation

58
Q

A patient taking regular steroids for sarcoid presents with hip pain - this is…

A

ostenecrosis of the bone ; can also be caused by chronic alcohol use and antiphospholipid antibody syndrome. Eval with MRI

59
Q

A patient presetns with slowly progressing back pain as well as sacroilitis - what other condition is she at risk for?

A

anterior uveitis

60
Q

Episcleritis should be suspected in patients with ..

A

RA and IBD

61
Q

A patient presents wtih anterior knee pain that is worse when climbing stairs. This is likely…

A

patellofemoral syndrome

62
Q

A patient presents with recurrent genital ulcers, anterior uveitis and skin lesions as well as a positive pathergy test. This is..

A

Behchet’s syndrome

63
Q

A young patient presents with bloody diarrhea, low back pain (sacroilitis) and positive P-ANCAs this is..

A

ulcerative colitis (IBD)

64
Q

A patient presents with back pain that is improved with sitting and leaning forward. What is this and how is it diagnosed?

A

neurogenic claudication from spinal stenosis - diagnose with MRI

65
Q

A young mother presents with pain in her thumb worsened with passive stretching of the thumb. This is..

A

De Quervain tenosynovitis

66
Q

A patient presents wtih 1 week of fever and joint pain in the small joints, pos RF. She stops feeling pain a few weeks later. This is..

A

viral arthritis

67
Q

An African American pt. presents with mild fevers, fatigue, blurry vision. X ray shows reticulonodular infiltrates and hilar adenopathy. This is..

A

sarcoid

68
Q

A patient who has pruritis in the shower presents with severe pain in his toe. This is…

A

polycythemia vera related gout

69
Q

A patient presents with recent constipation, fatigue and frequent urination. His serum levels show elevated Ca and he has a stiff knee. Knee aspiration will show

A

positively bifurigent crystals - he has hyperparathyroidism and therefore is at risk of pseudogout

70
Q

A patient presents with a tender mass in the right popliteal fossa. This is likely…

A

Baker’s cyst caused by inflamed synovium

IM (24 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions