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AMK 2023 > Rheumatology > Flashcards

Rheumatology Flashcards

1
Q

In Fibromyalgia how long is the pain present before diagnosis can be made

A

3 Months

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2
Q

What Rheum condition presents with characteristics such as: Stiff after sleep, worsened by cold, stress and activity, Pain in back and neck worse.

A

Fibromyalgia

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3
Q

What conditions are associated with fibromyalgia?

A

Chronic fatigue syndrome, restless leg syndrome, Depression and anxiety, Irritable bladder, IBS, Migraines, painful periods,

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4
Q

What Rheum condition presents with characteristics such as: Flu-like illness followed by; weakness, back and neck pain and stiffness, tender muscle and tendons

A

Fibromyalgia

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5
Q

What is the Goal of pharmacological intervention in fibromyalgia

A

To aid associated symptoms like depression and difficulty sleeping

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6
Q

Name three management options for fibromyalgia

A

CBT, exercise and heated pools

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7
Q

what drugs are associated with drug induced lupus?

A

chlorpromazine, Methyldopa , Hydralazine, Isoniazid, d-penicillamine, minocycline

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8
Q

What Infection is linked to causing SLE

A

Epstein barr virus

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9
Q

what is the characteristics of the SLE rash

A

malar (butterfly) rah precipitated by sunlight and sparing of the naso-labial folds. erythmatous and well demarcated

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10
Q

What Cardiac conditions are linked with SLE

A

pericarditis, HTN and endocarditis

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11
Q

name three Respiratory conditions associated with SLE

A

Fibrosing alveolitis, Pulmonary Emboli

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12
Q

What renal conditions are linked with SLE

A

nephritis and GN

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13
Q

What antibody should be tested for diagnosis of drug induced lupus

A

anti-histone

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14
Q

What antibody Is 30% prevalent in polymyositis and dermatomyositis

A

Anti-Jo

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15
Q

What antibody Is prevalent in scleroderma

A

anti-centromere (70%)

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16
Q

ds-DNA is 70 % prevalent in what condition

A

SLE

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17
Q

what antibody is most sensitive to SLE

A

ANA

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18
Q

what antibodies is most specific to SLE

A

Anti-dsDNA and Anti smith

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19
Q

what antibodies are prevent in both SLE and Sjögren’s

A

Anti-Ro and anti La

20
Q

What antibodies are most prevalent in sjögrens

A

Anti-Ro and anti La

21
Q

anti-sm antibodies are more prevalent in what ethnic group in SLE patients

A

black African

22
Q

What Rheum condition presents with characteristics such as: dry eyes, dry mucosa, fatigue and arthralgia

A

Sjögren’s

23
Q

name three conditions associated with Sjögren’s

A

autoimmune thyroid disease, coeliacs, Primary bilary cirrhosis

24
Q

What cancers are associated with Sjögren’s

A

B-call lymphoma, non-hodgkins lymphoma and parotid tumour

25
Q

What clinical test contributes to diagnosis of Sjögren’s?

A

Schirmers test

26
Q

What result in the Schirmers test is suggestive of Sjögren’s ?

A

less than 5mm/5mins

27
Q

What results in antibody testing is suggestive of enteropathic arthritis

A

Seronegative

28
Q

what antigen positive is heavily associated with enteropathic arthritis ?

A

HLA-D27

29
Q

What Rhuem condition presents with only Symmetrical proximal muscle weakness and Skin lesions

A

Dermatomyositis

30
Q

What three cancers are most associated with Dermatomyosistis

A

Lung, breast and ovarian

31
Q

Photosensitive macular rash over back and shoulders is indicative of what Rheum condition

A

Dermatomyositis

32
Q

It is a reddish-purple rash on the upper eyelids that is usually bilateral is what rash

A

Heliotrope rash

33
Q

A heliotrope rash is in what condition

A

juvenile dermatomyositis

34
Q

What systemic vasculitis affects medium sized vessels

A

Polyarteritis Nodosa and Kawasakis disease

35
Q

What systemic vasculitis affects large sized vessels

A

Giant cell arteritis and takayasus arteritis

36
Q

Name 4 conditions that are ANCA positive

A

Microscopic polyangitis, granuloatosis with polyangitis, eosiniophillic granulomatosis with polyangitis, HSP

37
Q

What vasculits presents with: sudden blindness, jaw claudication and limb pain

A

Giant cell arteritis

38
Q

What vasculits presents with: reduced BP and pulse in one arm and renal dysfunction

A

takayasus arteritis

39
Q

What vasculits presents with: foot drop, abdomen pain and haemorrhage, gangrene, glomeronephritis, rash

A

polyarteritis Nodosa

40
Q

What vasculits presents with: conjunctivitis, dry sore mouth, polymorphic rash, red and swollen palms,

A

kawasakis

41
Q

What vasculits presents with: ENT symptoms (Epitaxisis, deafness), GN, neuropathy, pulmonary fibrosis

A

granulomatosis wth Polyangitis

42
Q

What vasculits presents with: rash, Late onset asthma, GN, peripheral neuropathy

A

eosiniophillic granulomatosis with polyangitis

43
Q

What vasculits presents with: Pulmonary fibrosis, GN, Rash, ENT symptoms, peripheral neuropathy,

A

Microscopic polyangitis

44
Q

What vasculitis presents predominantly in turkey, Japan and Iran

A

Behçets disease

45
Q

What vasculitis presents with genital ulcers, Eye lesions, skin lesions and Oral ulcers

A

Behçets disease

AMK 2023 (16 decks)

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