Oncology

Question 1

what Type of leukaemia affects T and B lymphocytes and plasma cells?

Answer 1

Lymphoid leukemia

Question 2

what Type of leukaemia affects the innate immune system including mast cells, neutrophils, monocytes and basophils ?

Answer 2

Myeloid leukemia

Question 3

what type of lymphoma will show Reed Sternberg cells ?

Answer 3

Hodgkins lymphoma

Question 4

PC: fatigue, weakness, dizziness, fever, easy bruising, reaccurant infection, night sweats.
Blood smear: Huge immature nucleus and cytoplasmic vacuolation

Answer 4

ALL

Question 5

PC: fatigue, weakness, dizziness, fever, easy bruising, reaccurant infection, night sweats.
Blood smear: diamond ring lymphocytes, fragile smear cells

Answer 5

CLL

Question 6

What type of Leukaemia presents with lymphocytes >5x10^9 and nodular and splenic involvement

Answer 6

CLL

Question 7

55 year old male with weight loss, anaemic symptoms, headache, abdominal pain
Bloods show raised basophils and eosinophils, with neutrophillia,
Low Hb, raised WBC and normal PLTs
most likely diagnosis

Answer 7

CML

Question 8

Referral from GP, cough, Rubbery painless cervical lymphadenopathy, genralised constitutional ‘B’ symptoms
most likely diagnosis

Answer 8

lymphoma

Question 9

77 year old PC: Hx of fragility fractures, anaemia, thrombocytopenia, Stage 3 kidney failure,
most likely diagnosis

Answer 9

Myeloma

Question 10

63 yr old with raised ESR, raised serum calcium, and hence-jones protein in urine is what diagnosis

Answer 10

multiple myeloma

Question 11

64F PC: post menopausal bleeding, with a BMI 35, and HX of PCOS. Most likely cancer

Answer 11

Endometrial cancer

Question 12

what is the most common endometrial cancer

Answer 12

adenocarcinoma 80%

Question 13

50F PC: vaginal discharge, coital bleeding and vaginal discomfort. FHx: 6 children with multiple partners, SHx of Smoking,
Most likely to be what cancer?

Answer 13

cervical

Question 14

50F white PC: vaginal discharge, coital bleeding and vaginal discomfort. FHx: 6 children with multiple partners, SHx of Smoking,
Most likely to be what cancer?

Answer 14

cervical

Question 15

50F PC: coital bleeding and urinary retention, rectal bleeding and haematuria. what invesitgations?

Answer 15

Chlamydia test, pregnancy test, Colposcopy, FBCs + LFTs, CT pelvis

Question 16

50F white PC: coital bleeding and urinary retention, rectal bleeding and haematuria. what invesitgations?

Answer 16

Calmydia test, pregnancy test, Colposcopy, FBCs + LFTs, CT pelvis

Question 17

78F white presents with vague abdominal pain, bloating and dyspepsia. BMI 32 HX: smoking, HRT, Menopause at 57, What investigation will most likely give diagnosis

Answer 17

CA125 (ovarian cancer)

Question 18

what are the risk factors for Fibroids?

Answer 18

HTN, Alcohol, Poor diet,

Question 19

what are the three types of fibroids?

Answer 19

intramural, submucosal and subserosal

Question 20

51F Afrocarribean PC: Abnormal perimenupausal bleeding with pelvic pain. Hx: HTN
What investigations? what diagnosis?

Answer 20

Preg test, Ultrasound, MRI, hysteroscopy, Endometrial smapling
Fibroids

Question 21

Obese 35F presents with dull ache, swollen abdomen, urinary urgency and frequency
Most likely dx diagnosis?

Answer 21

benign ovarian tumor, (age makes this more likely than cancer)