Rheumatoid Arthritis

Question 1

2010 ACR/EULAR criteria for the classification of RA

Answer 1

Number and site of involved joints
Serological abnormality
Elevated acute phase response
Symptom duration

Question 2

Assessment tools for RA - radiology

Answer 2

Sharp score

Larsen index

Question 3

Assessment tools for RA - disease activity

Answer 3

Disease activity score (DAS)
ACR response criteria
EULAR response criteria

Question 4

Assessment tools for RA - functional status

Answer 4

Health assessment questionnaire (HAQ)

Question 5

Radiological evidence of early RA

Answer 5

Soft tissue swelling 
Periarticular osteopenia
Loss of cartilage 
Narrowing of joint space 
Juxta-articular erosions
Large cystic erosions

Question 6

DAS28

Answer 6

Provides a number on a scale 1 - 10 which indicates to current activity of the disease
>2.6 remission
>3.2 low disease activity
5.1 - 10 high disease activity

Question 7

HADQI

Answer 7

Patients report how much difficulty they are having performing various activity and score 0 - 3

Question 8

csDMARDs

Answer 8

Methotrexate, gold, sulfasalazine, hydroxychloroquine, leflunomide

Question 9

Hydroxyhchloroquine interferes with

Answer 9

cell’s ability to degrade and process proteins

Question 10

Methotrexate interferes with

Answer 10

production of tetrahydrofolate and de novo synthesis of purines