Chronic inflammation Flashcards
1
Q
DMARDs
A
Inhibit macrophage activation
Inhibit cell proliferation
Decreased release of pro inflammatory cytokines and ROS
2
Q
Endogenous corticoids
A
Mineral corticoids and glucocorticoids
3
Q
Mineralcorticoids
A
Affect water and electrolyte balance
4
Q
Glucocorticoids
A
Affect carbohydrate and protein metabolism
Anti-inflammatory and immunosuppressive effects
5
Q
Cushings syndrome
A
Excessive glucocorticoids
6
Q
Conns syndrome
A
Excessive mineral corticoids
7
Q
Interleukin-1 (IL-1) effects
A
Increase synthesis of COX-2 and iNOS
Increase expression of VCAM and ICAM
Increase bone erosion (osteoclasts, RANKL)
8
Q
TNF effects
A
Stimulates recruitment of neutrophils and monocytes to site of infection and their activation
