rhabdomyolysis Flashcards
1
Q
what
A
condition where skeletal muscle breaks down and releases breakdown productsi into blood
usually triggered by event causing muscle to breakdown
2
Q
myocyte apoptosis releases..
A
myolgobin
potassium
phosphate
creatinine kinase
3
Q
what is most dangerous release product
A
potassium as hypokalaemia can cause cardiac arrythmias
4
Q
how are kidneys affected
A
breakdown products are filtered by and injure kidneys
myoglobin esp bad
results in AKI
5
Q
causes
A
prolonged immobiliy
extremely rigorous exercise
crush injuries
seizures
6
Q
presentation
A
muscle aches and pain oedema fatigue confusion myoglobinurea - red/brown urine
7
Q
investigations
A
CK - highly raised
dipsitck - myoglobinurea will cause blood positive result
u&Es
ECG
8
Q
Mx
A
IV fluids
treat complications e.g. hyperkalaemia
