acute tubular necrosis Flashcards
1
Q
what
A
damage and death of epithelial cells of renal tubules
most common cause AKI
2
Q
why does damage occur to kidney cells
A
ischaemia or toxins
3
Q
is it reversible
A
yes - epithelial cells have ability to regenerate
4
Q
recovery time
A
7-21 days
5
Q
causes: ischeamia
A
2ry to hypoperfusion in
- shock
- sepsis
- dehydration
6
Q
causes - toxin damage
A
contrast dye
gentamicin
NSAIDs
7
Q
urinalysis finding
A
muddy brown casts
may also be renal tubular epithelial cells in urine
8
Q
Mx
A
supportive
IV fluids
stop nephrotoxic medications
treat complications