acute tubular necrosis Flashcards

1
Q

what

A

damage and death of epithelial cells of renal tubules

most common cause AKI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

why does damage occur to kidney cells

A

ischaemia or toxins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

is it reversible

A

yes - epithelial cells have ability to regenerate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

recovery time

A

7-21 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

causes: ischeamia

A

2ry to hypoperfusion in

  • shock
  • sepsis
  • dehydration
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

causes - toxin damage

A

contrast dye
gentamicin
NSAIDs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

urinalysis finding

A

muddy brown casts

may also be renal tubular epithelial cells in urine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Mx

A

supportive
IV fluids
stop nephrotoxic medications
treat complications

How well did you know this?
1
Not at all
2
3
4
5
Perfectly