benign prostate disease + urinary tract obstruction Flashcards
BPE
benign prostatic enlargement
BPH
benign prostatic hyperplasia
BPO
benign prostatic obstruction
BOO
bladder outflow obstruction
LUTS
lower urinary tract symptoms
benign prostatic hyperplasia
fibromuscular and glandular hyperplasia
affects transition zone
part of male ageing
LUTS: voiding (obstruction)
hesitancy
poor stream
terminal dribble
incomplete empytin g
LUTS: storage (irritative)
frequency
nocturia
urgerny
+/- urge incontinence
physical exam
abdnomen - palpable bladder?
penis - external urethral meatal stricture, paraphimosos
DRE - prostate
urinalysis
Ix
MSSU
PSA
urea and creatinint
USS
management BPO
watchful waiting
medical therapy - alpha blockers, 5 alpha reductase inhibitors
surgical - TURP, prostatecotmy, alblation
alpha blockers
main treatment of LUTS due to BPO
cause smooth muscle relaxation and antagonise dynamic element to prostatic obstruction
5-alpha reductase inhibitors
converts testosterone to dihydrotestosterone
what do 5-alpha reductase inhibitors do
reduce prostate size and risk progression BPE
reduce LUTS
TURP
transurethral resection of prostate
gold standard - v effective releiving symptoms