Rh Blood Group

Question 1

Codes for RHD and RHCE genes

Answer 1

Chromosome 1

Question 2

Frequency of Antigens:

D antigen: ___%
d antigen: ___%

Answer 2

Frequency of Antigens:

D antigen: 85%
d antigen: 15%

Question 3

Fischer Race Nomenclature

Answer 3

Based of DCE genes (DCE)

Question 4

Weiner

Answer 4

Based on agglutinogen that contain a series of blood factor (Rh-hr)

Question 5

Rosenfield

Answer 5

No genetic basis.
Based on Numerical terms

Question 6

RHAG

Answer 6

gene that codes for Rh associated glycoprotein

Rh precursor substance - coexpressor and express RhD proteins

Question 7

RhD presursor substance

Answer 7

RhAG

Question 8

R1r

Answer 8

Most common phenotypes of Whites

Question 9

R0r

Answer 9

Most common phenotype of Blacks

Question 10

Phenotype with MOST to LEAST amount of D antigen

Answer 10

D– > R2R2 > R1R1 > R1r/R0r > R1r’ or R0r’

Question 11

R2R2

Answer 11

Commonly encountered genotype with high amount of D antigen

Question 12

Immunogenicity of Rh Ag

Answer 12

D > c > E > C > e

Question 13

Asian Phenotypes

Answer 13

R1 > R2 > r > R0

Question 14

Black Phenotypes

Answer 14

R0 > r > R1 > R2

Question 15

Rh antigens Position and Enzymes - C/c

Answer 15

103rd position

Serine - C
Proline - c

Question 16

Rh antigens Position and Enzymes - E/e

Answer 16

226th position

Proline - E
Alanine - e

Question 17

D antigen is immunogenic when exposed to ____ mL of blood.

Answer 17

<0.1 ml of blood

Question 18

Weak D

Answer 18

Complete but few in numbers

Question 19

Partial D/D Mosaic

Answer 19

Incomplete or Missing D antigen ( RHD – RHCE – RHD)

Question 20

RhD positive individual that develops anti-D is present in a _______________ individual.

Answer 20

Partial D/D Mosaic

forms anti-D directed towards the missing portion/epitope of the D Ag

Question 21

Partial D individual as a Patient is typed as _________ .

Answer 21

Rh negative

to prevent formation of anti-D once exposed to a complete RhD antigen

Question 22

Partial D individual as a Donor is typed as _________ .

Answer 22

Rh Positive

Question 23

Del

Answer 23

RBCs with extremely low numbers of D antigen

Question 24

Test for Weak D Testing

Answer 24

IAT

Question 25

Forms anti-Rh17 if exposed to normal cells

Answer 25

D--

Question 26

Forms Rh29

Answer 26

Rh null phenotype

Question 27

Rhnull RBC

Answer 27

Stomatocytosis

Question 28

Rhmod

Answer 28

Partial suppression of Rh gene expression

Question 29

Rh Ab

Answer 29

IgG (IgG1 and IgG3)

Question 30

Weak D is common in ________.

Answer 30

Blacks

Question 31

Rhnull is common in _______.

Answer 31

European

Question 32

Warm autoantibodies appear to have "____________" specificity

Answer 32

Warm autoantibodies appear to have **"anti-e" specificity**

Question 33

Rh null phenotype Diagnosis

Answer 33

Rh null phenotype Diagnosis *** Mild compensated Hemolytic Anemia** * Reticulocytosis * Slight-decrease in Hb and Hct * Increase HbF * Decrease Serum Haptoglobin * Increase Bilirubin *** Stomatocytosis***