Revise

Question 1

What are 3 conditions that haemoglobin’s affinity for oxygen is dependent on?

Answer 1

Partial pressure of oxygen
Haemoglobin saturation
Partial pressure of carbon dioxide

Question 2

How can haemoglobin changing shape affect its affinity for oxygen?

Answer 2

1st oxygen binds haemoglobin which causes change in shape, allowing more oxygen to bind. Cooperative binding is involved

Question 3

What is the pulmonary vein connected to & what does it do?

Answer 3

Left atrium
Bring oxygenated blood back from lungs to heart

Question 4

What is the Bohr effect?

Answer 4

The more CO2 there is, the lower the pH, the greater the haemoglobin shape change, the more readily O2 is unloaded, the more O2 is available for respiration

Question 5

How does low pH affect haemoglobin?

Answer 5

Tertiary structure of haemoglobin changes, decreasing its affinity for oxygen so increasing the dissociation of oxygen