Review Slides - patho Flashcards
What happens to the body during anaphylaxis
shock, decreased blood pressure, vasodilation, bronchoconstriction
Chain of infection
infectious agent –> reservoir –> portal of ext –> mode of transmission –> portal of entry –> susceptible host
What is the type 1 hypersensitivity reaction
immediate
What happens during the type 1 immediate hypersensitivity reaction
IgE binds with a mast cell –> combine with antigen –> secrete histamine –> vasodilation
What is the type 2 hypersensitivity reaction
cytotoxic
What happens during the type 2 cytotoxic hypersensitivity reaction
IgS targets cells with antibodies, leading to cell destruction and phagocytosis
What is the type 3 hypersensitivity reaction
immune complex
What happens in the type 3 immune complex hypersensitivity reaction
an antigen binds with IgS, creating a tissue complex and causing organ dysfunction
What is the type 4 hypersensitivity reaction
delayed
What happens in the type 4 delayed hypersensitivity reaction
T-cells don’t attack for days after exposure to an antigen
Pathophysiology of autoimmune disorders
T-cells and immunoglobulins cannot distinguish between surface cell markers
Why does chronic inflammation hinder healing
prostaglandins are released and damage tissue
Wound healing stages
inflammation, proliferation, remodeling
Bone healing stages
fracture, granulation tissue formation, callus formation, lamellar bone deposition, remodeling
Anoxic encephalopathy
brain cell damage due to a decrease in oxygen in brain
