Retinal Pathways Flashcards

1
Q

Horizontal cells are responsible for:

A

Lateral inhibition

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2
Q

Horizontal cells are specialized retinal cells that run:

A

Perpendicular to the photoreceptors and make contact with photoreceptors and bipolar cells

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3
Q

Amacrine cells have been implicated in:

A

Contrast enhancement and temporal sensitivity ( detecting light patterns that change over time)

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4
Q

Amacrine cells synapse horizontally between:

A

Bipolar cells and retinal ganglion cells

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5
Q

Bipolar cell:

A

A retinal cell that synapses with one or more rods or cones (not both) and with horizontal cells, and then passes the signals on to ganglion cells

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6
Q

Diffuse bipolar cell:

A

A bipolar cell that receives input from multiple photoreceptors

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7
Q

Midget Bipolar cell:

A

A small bipolar cell that receives input from a single cone

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8
Q

P Ganglion Cells:

A

-Connect to the parvocellular pathway
-Receive input from MIDGET bipolar cells

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9
Q

The parvocellular (“small cell”) pathway is involved in:

A

-Fine visual acuity, color and shape processing.

-Poor temporal resolution, but good spatial resolution

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10
Q

M ganglion cells connect to:

A

The magnocellular pathway

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11
Q

M ganglion cells receive input from:

A

Diffuse bipolar cells

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12
Q

Magnoellular “large cell” pathway is involved in:

A

Motion Processing

Excellent temporal resolution, but poor spatial resolution

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13
Q

126 million photoreceptors converge to

A

1 million ganglion cells

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14
Q

Average of 50 rods to

A

one bipolar cell

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15
Q

Average of 6 cones to :

A

one DIFFUSE bipolar cell

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16
Q

Cones in fovea have:

A

1 to 1 relation to midget bipolar cells

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17
Q

All cone foveal vision results in:

A

high visual acuity

(one to one wiring leads to ability to discriminate details)
(trade off is that cones need more light to respond than rods)

18
Q

Receptive field:

A

The region on the retina in which stimuli influence a neuron’s firing rate

19
Q

What are the two types of retinal ganglion cells?

A

Parasol RGC’s (bigger)
Midget RGC’s (smaller)

20
Q

Output of center-surround receptive fields changes depending on area stimulated:

A

Highest response when only the excitatory area is stimulated

Lowest response when only the inhibitory area is stimulated

Intermediate responses when both areas are stimulated

21
Q

Why center-surround receptive fields?

A
  • each ganglion cell will respond best to spots of a particular size (and respond less to spots that are too big or too small)
    -retinal ganglion cells act like a filter for information coming to the brain
22
Q

Retinal ganglion cells are most sensitive to:

A

Differences in the intensity of light between center and surround and are relatively unaffected by the average intensity

23
Q

Luminance variations tend to be :

A

SMOOTH within objects and SHARP between objects

24
Q

Center surround receptive fields help to :

A

emphasize object BOUNDARIES

25
Q

P (parvocellular) ganglion cells:

A

Small receptive fields
High acuity
Work best in high luminance situations
Sustained firing

26
Q

P (parvocellular) ganglion cells provide information mainly about:

A

The CONTRAST in the retinal image

27
Q

M (magnocellular) cells:

A

Large receptive fields, low acuity, work best in low luminance situations, burst firing

28
Q

M (magnocellular) ganglion cells provide information about:

A

how an image changes over time

29
Q

Three lightness perception phenomena explained by lateral inhibition:

A
  • The Hermann Grid
  • Mach Bands
  • Simultaneous Contrast
30
Q

The hermann grid:

A

seeing spots at an intersection

31
Q

Mach Bands:

A

Seeing borders more sharply

32
Q

Simultaneous contrast:

A

Seeing areas of different brightness due to adjacent areas

33
Q

For the Hermann grid effect, signals from __ may cause effect

A

bipolar cells

34
Q

Explain how the Hermann grid effect happens:

A

Receptors stimulated by dark areas inhibit the response of neighbouring cells receiving input from white area

The lateral inhibition causes a reduced response which leads to the perception of gray

35
Q

What are Mach Bands?

A

People see an illusion of enhanced lightness and darkness at borders of light and dark areas
(Actual physical intensities indicate this is not in the stimulus itself)

36
Q

How does lateral inhibition explain our perception of Mach Bands?

A

The lateral inhibition in our circuit has created a neural
patter that looks like the Mach bands we perceive.
* A circuit similar to this one, but of much greater
complexity, is probably responsible for the Mach bands
that we perceive.

37
Q

What is simultaneous contrast:

A

People see an illusion of changed brightness or color due to effect of adjacent area

An area that is of the same physical intensity appears:
-lighter when surrounded by a darker area
-darker when surrounded by a light area

38
Q

Explain simultaneous contrast in terms of lateral inhibition?

A

Receptors stimulated by bright surrounding area send a large amount of inhibition to cells in center –> resulting perception is of a darker area than when this stimulus is viewed alone

Receptors stimulated by dark surrounding area send a small amount of inhibition to cells in center –> resulting perception is of a lighter area than when this stimulus is viewed alone

39
Q

Lateral inhibition __ explain simultaneous contrast

A

cannot entirely

40
Q

macular degeneration:

A

damage to photoreceptors at the center of the retina

41
Q

retinitis pigmentosa

A

gradual degeneration of the photoreceptors over many years–> night blindness