Respiratory System II Flashcards

1
Q

Is the secondary lobule of miller present of the lung or pleural tissue

A

pleura

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2
Q

What structures are held within the secondary lobules of miller

A

terminal bronchioles, respiratory bronchioles, alveolar ducts, alveolar sacs, and alveoli

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3
Q

Respiratory bronchioles are lined by… epithelium

A

ciliated cuboidal

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4
Q

T/F: The epithelium on the respiratory bronchiole is discontinuous

A

T, the epithelium is incomplete where the alveoli come off of the respiratory bronchiole

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5
Q

T/F: The alveoli coming off of the respiratory bronchioles are lined by the same type of epithelium

A

F, they are lined by simple squamous epithelium

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6
Q

In addition to the ciliated cuboidal cells, what other cells lie in the epithelium of the respiratory bronchioles

A

clara cell

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7
Q

A respiratory bronchiole divides to form two…

A

alveolar ducts

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8
Q

The alveolar duct is lined by…

A

simple squamous epithelium

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9
Q

What are interalveolar septa

A

walls between alveoli

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10
Q

Interalveolar septa are rich in…

A

BV and elastic fibers (responsible for elasticity of the lung)

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11
Q

Destruction of the inter alveolar septum is a sign of…

A

emphysema

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12
Q

Role of Pores of Kohn

A

help equilibrate pressure and aid in communication between adjacent alveoli

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13
Q

What passes in and out of pores of Kohn

A

dust cells

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14
Q

What are the two types of cells in the alveolus

A

Type I and II pneumocytes

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15
Q

What type of cell is the type I pneumocyte

A

simple squamous epithelial cell type

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16
Q

Describe the distribution of organelles in the type I pneumocyte (TIP)

A

Organelles are clustered around nucleus (leaving attenuated lateral surfaces)

17
Q

TIP contains…vesicles to collect debris from the alveolar lumen to transfers them to…

A

pinocytotic…macrophages

18
Q

T/F: The TIP doesn’t participate in the blood-air barrier

A

F

19
Q

What is the function of the blood-air barrier

A

external respiration (therefore the barrier must be thin)

20
Q

What is the blood air barrier comprised of

A

TIP, single basal lamina created by the fusion of the lamina of the alveolar epithelial and capillary endothelial cell, and the simple squamous epithelial cell of the capillary

21
Q

T/F: TIPs comprise 95% of alveolar surface and are those more numerous than TIIPs?

A

F TIIPs are more numerous

22
Q

Morphology of TIIP

A

Cuboidal cell with microvilli on apical surface

23
Q

Key morphological feature of TIIP seen with EM

A

lamellar body

24
Q

What is the sectretory product of the lamellar body

A

surfactant

25
Q

Role of surfactant

A

prevents the alveoli from deflating during expiration

26
Q

Mitosis of TIIPs leads to…

A

TIPs

27
Q

Where are dust cells commonly found

A

interalveolar septum or lumen

28
Q

Macrophages in the lung tissue have surface receptors for…and….

A

IgG and Cb3

29
Q

Dustcells produce chemoattract factor for… in the presence of antigens

A

neutrophils

30
Q

Systemic circulation: Bronchiole arteries supply…

A

bronchi and bronchioles

31
Q

Alveoli are supplied by

A

diffusion through capillary beds

32
Q

Branches of the pulmonary arteries are found…

A

next to bronchi and bronchioles

33
Q

T/F: Plumonary veins do not run adjactent to bronchi/bronchioles

A

T That run independently

34
Q

Where would you expect to find capillaries in the lung

A

underlying the alveoli for gas exchange

35
Q

Where would you expect to find bronchiole a.

A

within the walls of bronchi and bronchioles