Respiratory System 5

Question 1

What is the pressure of gas inversely related to?

Answer 1

It’s volume

Question 2

What the concentration of dissolved gas vary directly with?

Answer 2

Partial pressure

Question 3

What’s the constant of proportionality called?

Answer 3

Solubility

Question 4

What does the solubility if a gas depend on?

Answer 4

The solvent (O2 is more soluble than oil in water) and (inversely) on temperature

Question 5

How much more soluble is carbon dioxide than oxygen in blood?

Answer 5

24 times more

Question 6

What is the partial pressure of a dissolved gas for?

Answer 6

So that externally applied pressure is required to prevent it coming out of solution

Question 7

What is oxygen content of blood?

Answer 7

The total amount of O2 carried in whole blood- it’s the sum of the O2 combined with haemoglobin inside erythrocytes and the O2 dissolved in plasma

Question 8

How much haemoglobin per litre of blood should the whole blood of healthy adults contain?

Answer 8

150g

Question 9

How much O2 can 1gram of haemoglobin bind?

Answer 9

1.34ml

Question 10

How much O2 can be bound to haemoglobin per litre of blood?

Answer 10

Up to 200ml

Question 11

What is the saturation of haemoglobin?

Answer 11

The amount of O2 actually bound to haemoglobin relative to the maximum amount that could be bound (200ml per L of blood)

Question 12

Under normal circumstances, how much is arterial blood saturated?

Answer 12

98%

Question 13

Per L of blood, realistically, how much O2 is bound to haemoglobin, and how much is dissolved in water?

Answer 13

197mL bound, 3mL in plasma

Question 14

What does anaemia reduce amount of O2 bound to haemoglobin to?

Answer 14

60mL per L of blood (less than half the normal level)

Question 15

What’s the result of anaemia reducing binding?

Answer 15

Total oxygen bound is substantially reduced despite the fact that haemoglobin remains around 98% saturated

Question 16

What happens during carbon monoxide poisoning?

Answer 16

Binding of O2 to haemoglobin is blocked by carbon monoxide, which has a higher affinity for haemoglobin, which causes a substantial reduction of oxyhaemoglobin saturation

Question 17

Is the CO2 dissociation curve or oxyhaemoglobim dissociation curve more linear?

Answer 17

CO2 dissociation curve

Question 18

How does O2 saturation affect CO2 content?

Answer 18

Increased O2 desaturation increases CO2 content, increased O2 saturation decreases CO2 content

Question 19

What is the CO2 content of whole blood compared to O2 content?

Answer 19

3 times greater

Question 20

Percentage of CO2 transported in blood?

Answer 20

9%

Question 21

% of CO2 transported as HbCO2?

Answer 21

13%,

Question 22

% CO2 transported in blood as HCO3-?

Answer 22

78%

Question 23

Overall gas exchange equation?

Answer 23

HbCO2+O2 to HbO2+CO2