Respiratory system Flashcards
Oxygen and CO2 exchange Olfaction Phonation Defense and Conditioning of air are all functions of what?
Respiratory system
What is the respiratory portion of the respiratory system
O2 and CO2 exchange
What is the conducting portion of the respiratory system
Olfaction
Phonation
Defense
And conditioning of air
True or false; along with warming and moistening the air, conditioning of the air refers to filtration of large to small particulate
true
True or false; the conduction portion of the respiratory system transport air to the respiratory portion
true
The surface epithelium of the nasal vestibule is made up of what?
keratinized stratified squamous epithelium
What kind of glands would you find in the vestibule of the nasal cavity
sweat and sebaceous
What kind of cartilage makes up the vestibule of the nasal cavity
hyaline
True or false; the mucociliary apparatus in the respiratory region of the nose filters medium size particulate
true
Where would you find seromucus glands in the nose?
lamina propria
The mucus portion of the serumucus glands of the nose functions to
humidify air
mucocililary clearance
The serous products produced by the seromucus glands of the nose act as a…
small particulate filter : Lysozyme (antibacterial) Interferons (antiviral) Cytokines (stimulate defense cells)
True or false; along with the seromucus glands, in the lamina propria of the nose you would expect to find a cavernous plexus with many large venules typically filled with blood
true
What are the 3 functions of the cavernous plexus in the lamina propria of the nose
Warm air
Humidify air
Provide defense (inflammation within lamina propria - stuffy nose - also increased blood -> increased O2 -> stimulate seromucus secretion -> runny nose)
True or false; the Paranasal sinuses are found in the ethmoid, sphenoid, frontal and maxilla bones; and connect to nasal cavity
true - connects through sinal ostia
Do the paranasal sinuses have a lamina propria?
yes; but is thin - has seromucus glands and quite vascular
What possible problem can arise due to small ostia connecting paranasal sinuses
inflammation can cause a blockage and subsequent sinus infection
What are the 3 subdivisions of the pharynx
Nasopharynx (superior)
Oropharynx (middle)
Laryngopharynx (inferior)
What kind of cells cover the surface epithelium of the mucosa of the nasopharynx
Respiratory epithelium - Mucociliary clearance
What kind of cells cover the surface epithelium of the mucosa of the oropharynx and Laryngopharynx
stratified squamous epithelium
True or false; the whole respiratory system has no muscularis mucosa
true
What would you expect to find in the lamina propria (loose ct.) of the nasopharynx
Pharyngeal and tubal tonsils
What would you expect to find in the lamina propria (loose ct.) of the Oropharynx
Lingual and palatine tonsils
Would you expect to see any tonsils in the lamina propria (loose ct.) of the Laryngopharynx
no
True or false; the submucosa of the pharynx = Pharyngobasilar fascia
true; Collagen in periosteum of basilar portion of occiput blends into wall of pharynx
What function does the submucosa of the pharynx (Pharyngobasilar fascia) have?
Adds support to 90 degree turn of head
What kind of muscle makes up the muscularis externa of pharynx? What is unique about the fiber arrangement?
All skeletal muscle
Unique because reverse pattern - Longitudinal inner and Circular outer (this arrangement also occurs in uterus)
True or false; the Adventitia of the pharynx = Buccopharyngeal Fascia
true
True or false; the Epimysium of buccinator muscle blends into the adventitia of pharynx (Buccopharyngeal fascia)
true
What kind of cells line the surface epithelium of the mucosa of the trachea
Respiratory epithelium
What is the arrangement of the muscularis mucosa in the trachea
there is no muscularis mucosa anywhere in the respiratory system
True or false; similarly to the respiratory region of the nose, the lamina propria of the trachea contains seromucus glands and is quite vascular
true
What is unique about the submucosa of the trachea
Contains hyaline cartilage C rings and blends with Lamina propria
What muscle would you expect to find with the muscularis externa of the trachea
Trachealis (smooth muscle)
What trends do you see decrease as you transition from trachea to bronchi
decrease: Amount of cartilage
Number of glands
Number of goblet cells
Height of epithelial layer
What trends do you see increase as you transition from trachea to bronchi
Increase: Smooth muscle and Elastic Ct.
Would you find cartilage in Bronchioles? What about seromucus glands
No to both; (Complete smooth muscle layer)
Would you expect to find clara cells in bronchioles?
yes
What is the last conducting portion of respiratory system?
Terminal bronchioles - Made of simple columnar/cuboidal with clara cells
What makes up the lamina propria of the terminal bronchioles
fibroelastic ct.
What is the first region of the respiratory portion of the respiratory system?
Respiratory bronchioles
Is the structure of the respiratory bronchioles similar to structure of terminal bronchioles?
yes; but respiratory have simple squamous epithelium (i.e. gas exchange is possible)
What is the general function of the alveolar ducts, alveolar sacs and alveoli
gas exchange
Which alveolar cell type is made of squamous cells, with zonula occludens and makes up 95% of alveolar surface
Alveolar type 1 - Type 1 pneumocyte
General function- gas exchange
Which alveolar cell type is made of cuboidal cells and makes up 5% of alveolar surface
Alveolar type 2 - Type 2 pneumocyte
While the alveolar type 1 cells function in gas exchange, what do the less numerous type 2 alveolar cells function in?
producing pulmonary surfactant
True or false; alveolar macrophages develop from monocytes
true
What is the region between two alveoli called?
Interalveolar septum (contains the 2 types of alveoli and basal lamina with small amounts of ct.)
What is the blood-gas barrier
region where oxygen and carbon dioxide pass between the air and blood
What makes up the blood-gas barrier?
Surfactant
Alveolar type 1 cells
Fused basal lamina between alveolar and endothelial cells
Chronic exposure to irritants would cause goblet cell numbers to what?
Increase- resulting in increased mucus
Chronic exposure to irritants would cause ciliated columnar cell numbers to what?
decrease - resulting in more congestion
Chronic exposure to irritants would cause seromucus glands to what?
Increase in size and increase secretion
What is the cause of respiratory distress syndrome in newborns?
too few mature alveolar type 2 cells
How could metaplasia occur due to chronic exposure to irritants
too much coughing - develop patches of stratified squamous epithelium instead of respiratory epithelium
What is emphysema? Is it reversible?
Decrease in elastin - decrease alveolar elasticity
Reduced surface for gas exchange
Irreversible