Respiratory Physiology & CPET

Question 1

What does Forced Socillation Technique (FOT) diagnose?

Answer 1

small airway obstruction.

2-5cm H2O oscillation forced through mouthpice, measuring resistance.

Question 2

Repeatability requirements for spirometry?

Answer 2

FEV1 and FVC within 0.15L of all 3 trials.

Question 3

Good start requirements for spirometry?

Answer 3

Extrapolated volume <5% of FVC or <0.15L

Question 4

For broncho-provocation challenge, what is a positive test?

Answer 4

Dose of the provocative substance that causes drop in FEV1 of 20%. Named PC20 or PD20.

Question 5

What medications can be continued for bronco-provocation challenge testing?

Answer 5

ICS, LTRAs.

Question 6

How do you test for needing oxygen for air travel?

Answer 6

• HAST = High Altitude Simulation Testing.
• Indicated if SpO2<92% or PaO2 <70.
• Tested by giving FiO2 15.1% for 20 minutes.
• If SpO2 falls below 85%, or PaO2 <55, then give O2 for air travel.

Question 7

MCID for 6MWT distance?

Answer 7

30m

Question 8

Flow-volume loops shift which direction for COPD vs which direction for restrictive disease? (Left vs right)

Answer 8

Left for COPD; right for restriction.