respiratory medicine Flashcards
inhalers are absorbed by which drug administration route?
topically
which 2 drugs may be used to improve airway patency?
bronchodilators
any-inflammatory
give 2 examples of bronchodilators
beta 2 agonists
anticholinergics
which 2 drugs may be given to prevent mast cell degradation?
chromoglycate
leukotriene receptor agonists
name 2 respiratory depressants
benzodiazepine
opioids
what is the main problem with a puffer?
high velocity suspension so not all medication makes it to the airway
which two other devices may be used instead of a puffer to ensure more drug reaches the lungs?
turbohaler
spinhaler
what is the benefit of using a spacer with an inhaler?
makes it easier to get straight to the lugs as lower velocity
which device may be used to deliver medication to a patients having an asthma attack or unable to use their inhaler?
nebuliser
beta agonists can be categorised into 2 groups, what are these?
short acting and long acting
what colour of inhaler contains short acting beta antagonist?
blue
name a short acting beta agonists
salbutamol
what colour of inhaler contains a long acting beta agonist?
green
name a long acting beta agonist
salmeterol
how do beta agonists aid breathing?
they dilate the lungs
compare short acting and long acting beta agonists
short (blue) - works a couple mins and effects last 4-6 hours
long (green) - works in an hour and effects last 12-15 hours
which type of beta agonist is used to TREAT bronchial constriction?
short acting
which type of beta agonist is used to PREVENT bronchial construction?
long acting
how may short acting beta agonists be administered?
inhaled
iv
orally
how may long acting beta agonists be administered?
inhaled
anticholinergics inhibit which receptors?
muscarinic
how do anticholinergics aid breathing?
cause bronchial dilation
reduce mucus secretion
how do corticosteroids aid breathing?
reduce inflammation in bronchial walls
most asthmatics take two different types of inhaler, what are these?
beta agonist and corticosteroid
what colours may corticosteroid inhalers be?
brown
orange
pink
is a patient is using a orange or pink inhaler do they have mild or severe asthma?
severe
do patients using blue and brown inhalers have mild or severe asthma?
mild
asthmatics that can’t be trusted to take both inhalers are given compound preparations, what do these contain?
inhaled steroid and long acting beta agonist
how does chromocglycate stop asthma?
it is a mast cell stabiliser
mast cell degranulation causes asthma and chromoglycate stops it
what 2 types of cough are there?
dry and productive
compare a dry cough and a productive cough
dry - doesn’t produce anything
productive - produces something (sputum)
what is a wheeze?
an expiratory noise on breathing out
what is a stridor?
inspiratory noise on breathing in (indicative of blockage to airway)
stress when breathing or uncomfortable breathing is known as?
dyspnoea
name some respiratory symptoms?
cough wheeze stridor dyspnoea pain