Respiratory: Leukotriene receptor antagonists Flashcards

1
Q

What are the two LTRA?

A

Montelukast and zafirlukast.

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2
Q

How do LTRA work?

A

They block the effects of cysteinyl leukotrienes in the airways. They are effective in asthma or when used alone or with an inhaled corticosteroid.

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3
Q

The LTRA may of benefit in exercise-induced asthma and in those with concomitant rhinitis, but they are less effective in what?

A

those with severe asthma who are also receiving high doses of other drugs.

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