Endocrine: Endometriosis Flashcards
What is endometriosis?
That is the growth of endometrial-like tissue outside the uterus.
Endometriosis is an oestrogen-dependent condition and is associated with what?
Menstruation
Endometriosis is typically associated with what symptoms? (3)
Pelvic pain.
Painful periods.
Subfertility.
Most drug treatments for endometriosis work how?
By suppressing ovarian function and are contraceptive.
What does surgical treatment in endometriosis aim to do?
Destroy or remove endometriotic lesions.
What should be considered as first-line management of endometriosis-related pain?
A short trial (such as 3 months) of paracetamol or an NSAID alone or in combination should be considered first-line.
Hormonal treatment (with a _______ ___ _________ or a ________) should be offered to women with suspected, confirmed or recurrent endometriosis
combined oral contraceptive or a progestogen
Hormonal treatment for endometriosis can reduce pain and has what effect on subsequent fertility?
No negative effect on fertility
For deep endometriosis involving the bowel, bladder or ureter, administraton of what for 3 months before surgery should be considered?
Gonadotropin-releasing hormones:
Goserelin (Zoladex) etc.
After laproscopic excision or ablation of endometriosis, what should be condisered to prolong the benefits of surgery and manage symptoms?
Hormonal treatment, with, for example a combined hormonal contraceptive.
A hysterectomy may be indicated if, for example the woman has what?
Adenomyosis (inner lining of the uterus breaks through the muscle wall of the uterus) or heavy menstrual bleeding that has not responded to other treatments.
If fertility is a priority, the management of endometriosis-related subfertility should have multidisciplinary involvement with input from a fertility specialist. Women with endometriosis who are trying to conceive should not be offered what? why?
Hormonal treatment, does not improve spontaneous pregnancy rates.
