Respiratory Histo Flashcards

1
Q

What is the function of the conduction portion of the respiratory system ?

A
  • warms, humidifies air
  • transmit ait
  • NO GAS EXCHANGE
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2
Q

What parts make up the conducting portion?

A

-nasal cavities -> paranasal sinuses -> nasopharynx -> trachea -> 1,2,3 bronchi -> bronchioles -> conducting bronchioles -> terminal bronchioles

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3
Q

What is the function of the respiratory portion of the respiratory system?

A

pass air to alveoli for gas exchange

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4
Q

What parts make up the respiratory portion ?

A

respiratory bronchioles -> alveolar ducts -> alveolar sacs

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5
Q

What reinforces the larynx?

A

thyroid and cricoid cartilages and small elastic cartilages

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6
Q

What is a main feature of the larynx

A

vocal colds

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7
Q

What kind of epithelium are the vocal folds?

what features are assoc. with them?

A

nonkeratinized stratified squamous

  • vocal l. supports
  • moved by vocalis m.
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8
Q

What kind of epithelium is the respiratory epithelium?

A

pseudo stratified ciliated columnar

contains ciliated, goblet, and basal cells

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9
Q

What is the purpose of the respiratory epithelium?

A
  • protect airway vis mucus

- move particles via cilia up and out

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10
Q

What are goblet cells?

A

modified columnar cells that produce mucigen granules

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11
Q

What are the 4 layers of the trachea?

A

1) mucosa (respirated. epi)
2) submucosa (dener CT than LP)
3) cartilaginous (c shaped hyaline cart rings)
4) adventitia (trachealis m. , CT that bind it to other structures)

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12
Q

What does tracheal epithelium contain?

A
  • pseudostrat
      • goblet cells
  • elastic, fiber rich LP
  • broncho Assoc. Lymph Tissue
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13
Q

What does tracheal submucosa contain?

A

+ + glands

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14
Q

What are the 4 layers of the bronchi?

A

1) epithelia
2) submucosa
3) muscular
4) adventitia

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15
Q

What is in the bronchi epithelial layer?

A

1) pesudostrat ciliated columnar
2) fewer goblet cells
3) + elastic fibers

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16
Q

What is in the bronchi submucosa layer?

A

loose/areolar CT
few glands
irregular cartilage pieces

17
Q

What is in the bronchi muscular layer?

A

cont. larger bronchi

loosely organ. smaller bronchi

18
Q

What is in the bronchi adventitia layer?

A

moderately dense CT

19
Q

What are the layers of the bronchioles?

A

1) epithelia
2) muscularis (SM)
no submucosa or cartilage

20
Q

What characterizes bronchiole epithelia?

A

larger cells = simple ciliated columnar
small cell = simple cuboidal

-few goblet
CLUB CELLS
- ^ elastic fibers

21
Q

What are the layers of terminal and respiratory bronchioles?

A

1) epithelia

2) muscularis

22
Q

What characterizes terminal and respiratory bronchiole epithelia?

A

simple cuboidal w/ club cells

23
Q

What are club cells ? What do they do?

A

-non-ciliated , dome shaped cells

  • secrete lipoprotein (prevent adhesion on expiration)
  • antimicrobial peptides
  • detox inhaled materials
24
Q

What are alveolar rings?

A

aggregates of SM, collagen, and elastic fibers that form rings around alveolar ducts

25
Q

What type of epithelia are alveolar ducts, rings, and sacs?

A

simple squamous epi

26
Q

What are the special cell types contain within alveoli?

A

Type 1 = gas exchange (simple squamous)
type 2 = surfactant (cuboidal/rounded)
–> precursor for type 1 &2

27
Q

What covers the pleura?

A

flattened mesothelium

28
Q

What is the purpose of pleura?

A
  • extend into the lung as fibrous septa, cont. w/ lung parenchyma
  • contain lymph vessels
29
Q

What composes the blood air barrier : internal to external ?

A
  • alveolar epithelium
  • fused alveolar basal lamina with capillary endothelia
  • capillary endothelia
30
Q

What is Asthma?

What do you see on a cellular level?

A
  • chronic inflammatory disease involving the airways
  • accomp. by bronchospasm
  • bronchiolar wall by eosinophil, lymphocytes, mast cells
  • thick bronchiolar epi. w/ + + goblet cells, thick basement membrane and hyperplstic SM
31
Q

Symptoms of asthma?

A

dyspnea, wheezing, productive cough

32
Q

What is emphysema?

A

permanent enlargement of air spaces distal to terminal bronchiole (dec surface area)

caused by chronic obstruction of airflow due to narrowing bronchioles accomplishments. by destruction of alveolar walls

33
Q

What is emphysema caused by?

A
  • smoking cigarettes
  • inhaling particulate matter (construction or coal)
  • autoimmune
34
Q

What is pnumonia?

A

inflammation fo lung tissue -> air space are filled w/ exudate contains WBCs (neutron) , RBC, fibrin

-red hepatization stage(looks like liver)

35
Q

What does the lung look like in pneumonia?

A

lung is heavy (exudate)

lung is firm and red (lack of air space)

36
Q

What are signs a symptoms of pneumonia?

A

fever & chills
productive cough
decreased breath sounds
crackles in lungs

37
Q

What is Bronchiolitis Obliterans?

Where does it occur?

A

intralaminal polyploid plug of granulation tissue (new CT formed from healing) in terminal and respiratory bronchioles

38
Q

What is Bronchiolitis Obliterans caused by?

Symptoms?

A

caused: inhalation of diacetyl ; lung transplant ; infections pneumonias, diffuse alveolar damage

symptoms : SOB, wheezing, dry cough