Respiratory Histo Flashcards

1
Q

What is the function of the conduction portion of the respiratory system ?

A
  • warms, humidifies air
  • transmit ait
  • NO GAS EXCHANGE
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2
Q

What parts make up the conducting portion?

A

-nasal cavities -> paranasal sinuses -> nasopharynx -> trachea -> 1,2,3 bronchi -> bronchioles -> conducting bronchioles -> terminal bronchioles

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3
Q

What is the function of the respiratory portion of the respiratory system?

A

pass air to alveoli for gas exchange

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4
Q

What parts make up the respiratory portion ?

A

respiratory bronchioles -> alveolar ducts -> alveolar sacs

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5
Q

What reinforces the larynx?

A

thyroid and cricoid cartilages and small elastic cartilages

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6
Q

What is a main feature of the larynx

A

vocal colds

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7
Q

What kind of epithelium are the vocal folds?

what features are assoc. with them?

A

nonkeratinized stratified squamous

  • vocal l. supports
  • moved by vocalis m.
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8
Q

What kind of epithelium is the respiratory epithelium?

A

pseudo stratified ciliated columnar

contains ciliated, goblet, and basal cells

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9
Q

What is the purpose of the respiratory epithelium?

A
  • protect airway vis mucus

- move particles via cilia up and out

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10
Q

What are goblet cells?

A

modified columnar cells that produce mucigen granules

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11
Q

What are the 4 layers of the trachea?

A

1) mucosa (respirated. epi)
2) submucosa (dener CT than LP)
3) cartilaginous (c shaped hyaline cart rings)
4) adventitia (trachealis m. , CT that bind it to other structures)

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12
Q

What does tracheal epithelium contain?

A
  • pseudostrat
      • goblet cells
  • elastic, fiber rich LP
  • broncho Assoc. Lymph Tissue
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13
Q

What does tracheal submucosa contain?

A

+ + glands

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14
Q

What are the 4 layers of the bronchi?

A

1) epithelia
2) submucosa
3) muscular
4) adventitia

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15
Q

What is in the bronchi epithelial layer?

A

1) pesudostrat ciliated columnar
2) fewer goblet cells
3) + elastic fibers

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16
Q

What is in the bronchi submucosa layer?

A

loose/areolar CT
few glands
irregular cartilage pieces

17
Q

What is in the bronchi muscular layer?

A

cont. larger bronchi

loosely organ. smaller bronchi

18
Q

What is in the bronchi adventitia layer?

A

moderately dense CT

19
Q

What are the layers of the bronchioles?

A

1) epithelia
2) muscularis (SM)
no submucosa or cartilage

20
Q

What characterizes bronchiole epithelia?

A

larger cells = simple ciliated columnar
small cell = simple cuboidal

-few goblet
CLUB CELLS
- ^ elastic fibers

21
Q

What are the layers of terminal and respiratory bronchioles?

A

1) epithelia

2) muscularis

22
Q

What characterizes terminal and respiratory bronchiole epithelia?

A

simple cuboidal w/ club cells

23
Q

What are club cells ? What do they do?

A

-non-ciliated , dome shaped cells

  • secrete lipoprotein (prevent adhesion on expiration)
  • antimicrobial peptides
  • detox inhaled materials
24
Q

What are alveolar rings?

A

aggregates of SM, collagen, and elastic fibers that form rings around alveolar ducts

25
What type of epithelia are alveolar ducts, rings, and sacs?
simple squamous epi
26
What are the special cell types contain within alveoli?
Type 1 = gas exchange (simple squamous) type 2 = surfactant (cuboidal/rounded) --> precursor for type 1 &2
27
What covers the pleura?
flattened mesothelium
28
What is the purpose of pleura?
- extend into the lung as fibrous septa, cont. w/ lung parenchyma - contain lymph vessels
29
What composes the blood air barrier : internal to external ?
- alveolar epithelium - fused alveolar basal lamina with capillary endothelia - capillary endothelia
30
What is Asthma? | What do you see on a cellular level?
- chronic inflammatory disease involving the airways - accomp. by bronchospasm - bronchiolar wall by eosinophil, lymphocytes, mast cells - thick bronchiolar epi. w/ + + goblet cells, thick basement membrane and hyperplstic SM
31
Symptoms of asthma?
dyspnea, wheezing, productive cough
32
What is emphysema?
permanent enlargement of air spaces distal to terminal bronchiole (dec surface area) caused by chronic obstruction of airflow due to narrowing bronchioles accomplishments. by destruction of alveolar walls
33
What is emphysema caused by?
- smoking cigarettes - inhaling particulate matter (construction or coal) - autoimmune
34
What is pnumonia?
inflammation fo lung tissue -> air space are filled w/ exudate contains WBCs (neutron) , RBC, fibrin -red hepatization stage(looks like liver)
35
What does the lung look like in pneumonia?
lung is heavy (exudate) | lung is firm and red (lack of air space)
36
What are signs a symptoms of pneumonia?
fever & chills productive cough decreased breath sounds crackles in lungs
37
What is Bronchiolitis Obliterans? Where does it occur?
intralaminal polyploid plug of granulation tissue (new CT formed from healing) in terminal and respiratory bronchioles
38
What is Bronchiolitis Obliterans caused by? | Symptoms?
caused: inhalation of diacetyl ; lung transplant ; infections pneumonias, diffuse alveolar damage symptoms : SOB, wheezing, dry cough