RESPIRATORY DISEASES Flashcards
what is the main function of the lungs?
gas exchange - inhaling oxygen that we need to oxidize macromolecules and removing carbon dioxide from our systems
where is gas exchange done?
alveoli
describe the roles of type 1 and type 2 alveoli cells
type 1: responsible for gas exchange
type 2: alveoli cells produce surfactant decrease surface tension to avoid the alveoli to collapse after exhalation
what is pleural effusion
accumulation of fluids in the pleura (layer that allows the lungs to expand) - causing shortness of breath
what is atelectasis
when lungs collapse
describe how nutrition impacts pulmonary function
- strength and endurance of respiratory muscles
- lung parenchyma –> increased incidence of pulmonary infection
- antioxidant protection - inadequate intake of antioxidants could lead to increased oxidative injury of the lung tissues
how do pulmonary functions impact nutrition>
- energy expenditure
- dietary intake (early satiety, anorexia)
what is cystic fibrosis?
autosomal recessive disease
- disease caused by genetic mutation which will impair the function of the CFTR (cystic fibrosis transmembrane conductance)
- CTFR is the sodium and chloride transport and so there will be abnormal transport leading to viscous/thick mucus secretion from epithelial surfaces
what is progressive lung disease?
inability to clear mucus from the lungs - mucus prevents entrance of different particles which will increase the change that we are exposed to possible infections
- chronic inflammation can lead to losing the functions of our lungs
- increased risk of infection
what is pancreatic insufficiency
malabsorption of fats
- steatorrhea (excessive amounts of fat in poops) –> poor growth pattern
- main causes of malnutrition in patients with CF
how are cystic fibrosis and diabetes related
(10-15% of adults)
- inflammation and accumulation of fibrous tissues in the pancreas - interferes with normal insulin production
what are the CF diagnosis
- all newborns are screened with serum testing
- fecal elastase test (elastase is a digestive enzyme) - may have pancreatic insufficiency if cannot find elastase in stools or lower values
- sweat chloride test (considered gold standard)
what are CF nutrition implications
- pancreatic insufficiency - malabsorption of dietary fat, fat soluble vitamins, and other nutrients
- increased energy requirements
- malnutrition –> stunted growth and inadequate weight gain in children
- osteoporosis –> from fat malabsorption (unabsorbed FA can form soaps and increase secretion of calcium, zinc, and magnesium
- hyponatremia - loss of sodium in sweat
what are you looking for in the assessment portion of CF?
- anthropometric measurements
- labs: glucose, albumin, electrolytes, serum vit A, D, E, K, and calcium
intervention for individuals with CF?
- high energy, high protein
- no need to restrict on fat
- liberalize high salt diet
- routine supplementation of fat soluble vitamins A, D, E, K
- breast milk recommended for first year of life