Respiratory Flashcards
1
Q
mechanism of action of cromolyn sodium
A
directly binds to mast cells thereby preventing their degredation and release of histamine and leukotrienes
2
Q
mechanism of theophylline
A
inhibits phosphodiesterase. This leads to an increase of cAMP, which causes bronchodilation.
3
Q
mechanism of ipratropium bromide
A
competitive inhibition of muscarinic receptors on airway smooth muscle (M3 type)
4
Q
mechnism of steroids
A
inhibits phospholipase A2 synthesis which decrease production of arachidonic acid and its metabolites = decreased inflammation
