Respiratory Flashcards

1
Q

Prophylaxis SBP

Indications
Abx

A
  • previous SBP
  • Protein <15 on ascitic tap or Child Pugh score >9 or hepatorenal syndrome

Oral ciprofloxacin

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2
Q

Main constituent of pulmonary surfactant

A

dipalmitoyl phosphatidylcholine (DPPC)

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3
Q

Pulmonary hypertension

treatment based on acute vasodilator testing

A

Acute vasodilator testing +ve: oral calcium channel blockers

Acute vasodilator testing -ve:
- prostacycline analogues (iloprost, treprostinil)
- endothelin receptor antagonists (bosentan, ambrisentan)
- phosphodiesterase inhibitors (sildenafil)

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4
Q

Endothelin

physiological effects

A

Vasoconstriction
Bronchoconstriction

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5
Q

Haldane effect
Respiratory physiology

A

Increasing pO2 means CO2 binds less well to Hb

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