Respiratory Flashcards
1
Q
Prophylaxis SBP
Indications
Abx
A
- previous SBP
- Protein <15 on ascitic tap or Child Pugh score >9 or hepatorenal syndrome
Oral ciprofloxacin
2
Q
Main constituent of pulmonary surfactant
A
dipalmitoyl phosphatidylcholine (DPPC)
3
Q
Pulmonary hypertension
treatment based on acute vasodilator testing
A
Acute vasodilator testing +ve: oral calcium channel blockers
Acute vasodilator testing -ve:
- prostacycline analogues (iloprost, treprostinil)
- endothelin receptor antagonists (bosentan, ambrisentan)
- phosphodiesterase inhibitors (sildenafil)
4
Q
Endothelin
physiological effects
A
Vasoconstriction
Bronchoconstriction
5
Q
Haldane effect
Respiratory physiology
A
Increasing pO2 means CO2 binds less well to Hb