respiratory Flashcards

1
Q

transthoracic plane is at what t level

A

t4

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2
Q

how many lobes on right lung

A

3

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3
Q

name of 4 paranasal sinuses

A

frontal, ethmoid, sphenoid and maxillary

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4
Q

what cartilage is the laryngopharynx made from

A

epiglottis is elastic and the rest are hyaline

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5
Q

what is the average lung capacity

A

5.9l

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6
Q

define intrinsic defence

A

non-immune mechanism of precenting infection

E.g: cough, sneezing, muco-ciliary clearance

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7
Q

define Innate / cell mediated immunity

A

Non-specific immune response present from birth

No memory

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8
Q

what do b cells form in the immune response

A

Specific to the antigen
Factories for antibodies
Activate other T-cells
Create memory cells

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9
Q

where is pressure highest in foetal circulation

A

Right heart

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10
Q

What are the groups of ribs?

A

1-7 true ribs
8-10 false ribs
10-12 floating ribs

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11
Q

Name the four nasal sinuses and where they drain into?

A

All middle meatus apart from sphenoid

frontal-middle meatus
ethmoidal - anterior middle meatus
sphenoid - sphenoidal recess
maxillary -middle meatus

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12
Q

Where does the nasolacrimal duct open into?

A

inferior meatus

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13
Q

Which is the largest meatus?

A

inferior meatus

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14
Q

What is the hiatus semilunaris

A

cresent shaped groove in the lateral wall of nasal cavity

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15
Q

Name three types of receptor involved in the control of ventilation, where they are situated and what affect their stimulation has?

A

juxtapulmonary receptors- chemical stimulation fast breathing

stretch receptors- pressure stimulated - causes shorter and shallower breathing

irritant receptors - throughout respiratory tract ,coughing in upper tract

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16
Q

What is the chloride shift and why is it needed?

A

C02 enters a RBC) some of it is converted into HCO3- which diffuses out of leaving H+ in cell, Cl- enters to keep the cell neutral

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17
Q

State three ways carbon dioxide is transported in the blood?

A

carbaminohaemoglobins
hco3-
dissolved in plasma

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18
Q

What cartilage is responsible for altering tension of the vocal cords?

A

arytenoid

19
Q

What does a shift to the left or right of an oxyhaemoglobin curve represent?

A

Left=higher affinity (fetal, to get oxygen from mother’s blood), right=lower (hummingbird)

20
Q

Name three things that shift the oxyhaemoglobin curve to the right

A

increase in temp
pco2
h+(ph)

21
Q

What is the primary way carbon dioxide Is transported in the blood

A

bicarbonate ions in the plasma

22
Q

State the normal arterial blood oxygen saturation

A

95-99%

23
Q

What is the average value for tidal volume, vital capacity, total lung capacity, respiratory rate

A

TV- 500ml
VC-4.5l
TLC- 5.7l
RR-15/min

24
Q

Describe the body’s response to altitude

A

Decrease PiO2, hyperventilation, increase minute ventilation, decrease PaCO2, initial alkalosis (compensated by renal bicarbonate secretion), tachycardia

25
Q

What is the Henderson-hasslebach equation?

and what catalyses it

A

Water+ carbon dioxide- H2CO3 -H+ + HCO3-

carbonic anhydrase

26
Q

What is the arterial blood pH at sea level and what happens at altitude

A

7.36-7.44

becomes more alkaline

27
Q

What are the three functions of (conchae?

A

Humidify 98%, heat regulator, filter, elevate, streamline and pressurnise

28
Q

What structure lies lateral to the ethmoidal air cells?

A

Orbit

29
Q

Where is the ventricle of the larynx?

A

Between the vocal folds and vestibular folds,

30
Q

When is surfactant first detectable in a fetus?

A

24 weeks

31
Q

what is conchea

A

bony structures inside your nose

32
Q

What is the correct order of the thyroid, hyoid and cricoid?

A

hyoid
thyroid
cricoid

33
Q

What happens to your pressure at altitude

A

Atmospheric pressure falls
Pio2 falls
FIO2 stays same

34
Q

Pathology of lungs at depth

A

Decompression sickness due to rapid decrease in pressure
Inert gas narcosis due to change in pressure
Arterial gas embolism blockage of blood supply to organs caused by bubbles in an artery

35
Q

Embryological phases

A

Embryonic 0-12 trachea and lung bud , epithelia
Pseudoglandular 5–16 everything apart from gas exchange
Canalicular 17-28 bronchioles and bronchus enlarge
Tissue becomes more vascular
Saccular - 28 terminal sacs develop
Alveolar late fetus after birth
Alveoli fully develop

36
Q

First breath

A
Fluid removed from lungs 
Air inhaled 
O2 stimulates pulmonary vasodilation 
Ductus arteriosus and venous constrict 
Foremen ovale close within 6 months after birth
37
Q

Nostril and nostril roof histology

A

Keratinising stratified squamous

Nostril roof - resp epithelium but no goblet cells

38
Q

What are type 2 pneumocytes

A

Synthesising cells of alveolar surfactant

39
Q

Wha does alveolar surfactant do

A

Lowers surface tension which keeps the alveoli from collapsing after exhalation and makes breathing easy

40
Q

histology of type 2 pneumocytes

A

cuboidal with apical microvilli.

41
Q

What is the Respiratory diverticulum

A

Week 4 of development

Outpocketing appears in the proximal part of primitive gut tube

42
Q

Lung buds

A

The diverticulum bifurcates into two buds , which become the left and right primary bronchi
Right then proliferate to give secondary and tertiary bronchi

43
Q

link between alveolar surfactant and premature babies

A

surfactant keeps alveoli open

if born more than two weeks premature there is not enough surfactant so they die cant keep themselves alive