Respi disorders in HIV Flashcards

1
Q

highest incidence of pneumonia among HIV px in

_____ months

A

1st 6 months of life

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2
Q

Prophylaxis up to 3 years
reduce mortality

A

primary isoniazid

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3
Q

when exposed to a close contact with TB

A

6 to 9 months secondary prophylaxis

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4
Q

respi symptoms not common but with tachypnea and chronic lung infiltrates

A

NTM

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5
Q

poor prognosis in NTM

A

Disseminated MaC

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6
Q

tx for NTM in HIV

A

Azith:clarith
Ethambutol

if dissem
add cipro, amik, rifampin, rifabutin, clofazamine

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7
Q

TB meds should be started when prior art

A

at least 2 weeks

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8
Q

primary prophylaxis in NTM

A

macrolides (immunosupressed)

dc if at 2 yo, stable on art >6 months

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9
Q

rsv sheds up to

A

90 days

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10
Q

may give this vaccine if not immunocompromised

A

measles
varicella

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11
Q

passive immunization
varicella
measles

A

measles ig within 6 days of exposure
varicella up to 96 hrs of contact

given to unvaccinated or immunosuppresed

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12
Q

most common pathogen identified

A

PCP

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13
Q

PCP highest incidence and peak at

A

1st yr of life
peaks at 3-6 months

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14
Q

strongly predicts PCP

A

high plasma HIV RNa

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15
Q

rapid decline in cd4 suggests

A

PCP

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16
Q

pCP labs

A

normal wbc, igG
elevated LDH

17
Q

reticulonodulr infiltrates of PCP

A

perihilar extending peripherally

other dx
pneumatocoeles
pneumothorax
pie

18
Q

tx of pcp

A

high dose co tri for 21 days

altern pentamidine

19
Q

co tri prophy

20
Q

found in lung biopsies of LIP

21
Q

diffuse infiltration if lymphocytes into interstitium

22
Q

media age of LIP

A

2.5 to 3 yo

23
Q

level of igG suggestive of LIp

A

more than 2500 mg/dl

24
Q

generalized lymphadenopathy
hepatosplenomegaly
clubbing
parotid enlargement

25
presumptive diagnosis of LIP
clinical reticulonodular for more than 2 months without another cause
26
most common tumor associated with HIV
Non hodgkins then KS Leiomyosarc Hodgkins
27
mosaic Attenuation inversely prop to fev1
BO
28
weeks to months after art unrecognized tb paradoxical worsening of lymphadenopathy, clinical and radio signs
iris immune reconstitution inflamm syndrome
29
airway obstruction requiring trache most common
severe ltb