Respi disorders in HIV Flashcards

1
Q

highest incidence of pneumonia among HIV px in

_____ months

A

1st 6 months of life

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2
Q

Prophylaxis up to 3 years
reduce mortality

A

primary isoniazid

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3
Q

when exposed to a close contact with TB

A

6 to 9 months secondary prophylaxis

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4
Q

respi symptoms not common but with tachypnea and chronic lung infiltrates

A

NTM

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5
Q

poor prognosis in NTM

A

Disseminated MaC

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6
Q

tx for NTM in HIV

A

Azith:clarith
Ethambutol

if dissem
add cipro, amik, rifampin, rifabutin, clofazamine

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7
Q

TB meds should be started when prior art

A

at least 2 weeks

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8
Q

primary prophylaxis in NTM

A

macrolides (immunosupressed)

dc if at 2 yo, stable on art >6 months

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9
Q

rsv sheds up to

A

90 days

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10
Q

may give this vaccine if not immunocompromised

A

measles
varicella

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11
Q

passive immunization
varicella
measles

A

measles ig within 6 days of exposure
varicella up to 96 hrs of contact

given to unvaccinated or immunosuppresed

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12
Q

most common pathogen identified

A

PCP

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13
Q

PCP highest incidence and peak at

A

1st yr of life
peaks at 3-6 months

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14
Q

strongly predicts PCP

A

high plasma HIV RNa

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15
Q

rapid decline in cd4 suggests

A

PCP

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16
Q

pCP labs

A

normal wbc, igG
elevated LDH

17
Q

reticulonodulr infiltrates of PCP

A

perihilar extending peripherally

other dx
pneumatocoeles
pneumothorax
pie

18
Q

tx of pcp

A

high dose co tri for 21 days

altern pentamidine

19
Q

co tri prophy

A
20
Q

found in lung biopsies of LIP

A

EBV

21
Q

diffuse infiltration if lymphocytes into interstitium

A

LIP

22
Q

media age of LIP

A

2.5 to 3 yo

23
Q

level of igG suggestive of LIp

A

more than 2500 mg/dl

24
Q

generalized lymphadenopathy
hepatosplenomegaly
clubbing
parotid enlargement

A

LIP

25
Q

presumptive diagnosis of LIP

A

clinical
reticulonodular for more than 2 months without another cause

26
Q

most common tumor associated with HIV

A

Non hodgkins

then KS
Leiomyosarc
Hodgkins

27
Q

mosaic Attenuation inversely prop to fev1

A

BO

28
Q

weeks to months after art
unrecognized tb

paradoxical worsening of lymphadenopathy, clinical and radio signs

A

iris

immune reconstitution inflamm syndrome

29
Q

airway obstruction requiring trache most common

A

severe ltb