resp 3 Flashcards

1
Q

what is the review slide of ventilation?

A
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2
Q

what is the slide of pressure changes during quiet breathing?

A
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3
Q

what does forced inspiration need?

A

additional accessory or secondary muscles become activated

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4
Q

what are the additional accessory muscles activated during forced inspiration?

A
  1. sternocleidomastoids: lift the sternum outward, contributing the water pump handle effect
  2. Neck and back muscles: elevate pectoral girdle increasing thoracic volume and extend back
  3. upper respiratory tract muscles: decrease airway resistance
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5
Q

what are the accessory muscle of forced expiration?

A
  1. abdominal muscles (contract and push organs up)
  2. internal intercostals and triangularis sterni
  3. neck and back muscles (lean over, decrease thoracic volume)
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6
Q

what is the slide of the pleura fluid and lungs?

A
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7
Q

lungs are _______________ to the diaphragm or thoracic wall

A

NOT DIRECTLY ATTACHED

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8
Q

How does the pleura create a more negative pressure?

A

PULLING LUNGS OUTWARD
-inspiratory muscles pull the parietal layer of pleura away from visceral layer, increasing the volume of the intrapleural cavity and thus decreasing intrapleural pressure

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9
Q

what is the intrapleural pressure during inspiration?

A

-intrapleural volume increases, which causes a drop in intrapleural pressure to an even more negative value
-lungs drawn to more negative intrapleural pressure and thus expand

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10
Q

what is the slide of all inspiration and expiration

A
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11
Q

an interruption in intrapleural pressure results in ____________

A

PNEUMOTHORAX (COLLAPSED LUNG)

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12
Q

what are the two types of pneumothorax?

A

traumatic
-parietal or visceral pleura

spontaneous
-lung and visceral pleura ruptures
-70% due to COPD (emphysema)

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13
Q

what is lung compliance?

A

-the degree of lung expansion at any time is proportional to the change in pressure
-but how much any given change in pressure expands the lungs depends on the stretchability or compliance of the lungs

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14
Q

what is lung elastase?

A

-the reciprocal of compliance, lung elastase (elastic recoil) is the ability to resist being deformed

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15
Q

what is pulmonary fibrosis and what is it an example of?

A

ex of decreased compliance
-formation or development of excess fibrous connective tissue in the lungs
-30,000 canadians affected

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16
Q

what causes pulmonary fibrosis?

A

-inhalation of pollutants: metals, asbestos, certain gases
-infections
-idiopathic: age related, genetic predisposition

17
Q

what is emphysema and what is it an example of?

A

ex of increased compliance
-proteolytic enzymes secreted by leukocytes attack alveolar tissue
-alveoli merge: loss of capillaries and reduction of surface are
-loss of lung recoil
-weakens alveoli walls creating airway resistance
-main cause: cigarette smoking

18
Q

what did scientists initially assume about lung compliance and elastase?

A

-assumed the major determinant of lung compliance and lung recoil must be elasticity of pulmonary cells and the extracellular matrix (elastin and collagen)
-in a healthy lung, this is not the case