Reproductive System Flashcards
What are the functions of the reproductive system?
Secretion of sex hormones
Production of gametes
Production of offspring
How many pairs of chromosomes do humans have?
23, for a total of 46
How many sets of chromosomes does a somatic cell have (and by the way what is a somatic cell?)
Two: 1 maternal, 1 paternal aka diploid (2n)
A somatic cell is any cell except gametes
How many chromosomes do gametes have?
23, they are haploid (n)
True or False: Gametes in a pair are identical
False. They are equivalent, they code for the same characteristics but one is maternal one is paternal
What is the term for the fusion of a sperm cell and egg cell?
Fertilization is the process
Zygote is the cell
What kind of cell is a zygote?
Diploid (2n)
What is the purpose of meiosis I?
To reduce the number of original chromosomes in half to prepare for fusion
What creates a unique set of chromosomes for each gamete?
Recombination aka Scrambling
True or false. Gametes do not go through Interphase prior to meiosis
False. They do
What happens in Prophase I of meiosis I?
Duplicates centriole pairs pair up forming tetrads
Crossing Over occurs: homologous chromosomes exchange equivalent segments
What does crossing over mean? When/How does it occur and what does it create?
Homologous chromosomes exchange equivalent segments
Occurs between non-sister chromatids during Prophase I
Creates a new chromosome that has some maternal and some paternal parts
What happens during Metaphase I?
Homologous chromosomes align in the center of the cell by miotic spindles
They are pulled apart into two separate cells
Independent Assortment - the side each chromosome lines up on is independent of other pairs
What happens during Anaphase I?
Homologous chromosomes are separated and move to opposite poles
What happens during Telophase I?
Two haploid (n) cells are formed
What happens during Telophase II?
Cytokinesis occurs and a total of 4 cells containing gametes (n) are made
What is the difference between the purpose of mitosis versus the purpose of meiosis?
Mitosis - Cell duplication to increase cell numbers. Makes sure cells stay the same.
Meiosis - Gamete production, produces genetic variation
When does synapsis occur? What is synapsis?
Prophase I of Meiosis. This is the process where two homologous chromosomes line up, allowing for crossing over
What are the 3 factors contributing to Genetic Recombination?
Crossing Over
Independent Assortment
Random Fertilization
How many possible genetic combinations are possible before crossing over?
n^23 means 8 million combos in each gamete
8mil x 8mil = 64 trillion possible combinations
What is gametogenesis?
The production of gametes. Begins in embryonic glands while in utero (amniotic life)
Where foes spermatogenesis take place?
In the seminiferous tubules in the testis, within sustentacular cells aka Sertori cells
What is the difference between spermatogenesis and spermiogenesis?
Spermatogenesis - Process if sperm cell production
Spermiogenesis - Spermatid maturation
When does spermatogenesis start?
Puberty, continues throughout life
What is the function of spermatogonia?
Goes through mitosis on the basal lamina at the blood-testicular barrier. For every one that goes through meiosis one remains behind to duplicate
What is important about the blood-testicular barrier?
Sperm cells are considered foreign by the body. If they crossed the barrier the immune system would develop antibodies for them
What are secondary spermatocytes?
Tetrad-containing cells (4 haploids not 2 diploids)
What happens in spermiogenesis?
Spermatids change shape, losing most of the cytoplasm and organelles
What are the hormonal effects of GnRH during spermiogenesis? What are the negative feedback loops?
GnRH > FSH > Sertoli cells > ABP increases spermatogenic cells’ ability to bind to testosterone
GnRH > LH > Leydig cells (aka interstitial cells) > testosterone production
FSH produces inhibin, which decreases FSH secretion
high testosterone levels decreases LH and GnRH secretion
What are the accessory male sex glands and their contribution to semen?
Seminal Vessicles - Left and Right, posterior base of bladder, 60% of volume. Rich in fructose
Prostate Gland - Base of bladder, 30% of volume, Alkaline solution to protect sperm from acidic environment of the vagina
Bulbourethral glands - beneath prostate on either side of membranal urethra. Alkaline fluid to neutralize urethra
What is semen?
A transport medium that protects and activates sperm
What do prostaglandins do?
Decrease cervical mucous viscosity and stimulates reverse peristalsis in the uterus
How much semen is ejaculated versus how much sperm?
2-5ml
Contains 20-150 million sperm
What are the anatomical characteristics of the penis?
Contains a urethra and 3 cylindrical bodies of erectile tissue
The corpus spongiosum expands to keep urethra open
The corpora cavernosa keeps the penis erect
What is the difference between the two phases of male sexual response?
Erection - Enlargement and stiffening of erectile tissue with blood. Vasodilation of corpus cavernosa is caused by PSNS
Ejaculation - Propulsion of semen by SNS
What are the two parts of ejaculation?
Emission - ducts and accessory organs rapidly contracting, bladder sphincter constricts
Expulsion - Muscles at the base of the penis undergo rapid contractions
What happens in utero concerning oogenesis?
All oogonia complete mitosis and become primary oocytes, they begin meiosis but arrest at prophase I
How many oocytes complete meiosis I?
About 400/250,000 primaries present at puberty
What is the primordial follicle?
A layer of simple squamous cells surrounding primary oocytes
What happens during puberty concerning oogenesis?
A primordial follicle becomes a primary follicle (cuboidal cells), which enlarges when antrum expands with fluid to become a Graafian follicle (these cells will become corpus luteum after expulsion of secondary oocytes
How is a secondary oocyte made?
A primary oocyte is activates and completes meiosis I but its unequal distribution of cytoplasm causes production of a secondary oocyte and a first polar body
True or false. All secondary oocytes go through meiosis ii
False. They only complete meiosis II if they are fertilized, otherwise arrest at metaphase II and are ovulated
What happens when an ovulated secondary oocyte is fertilized?
A sperm cell merges with it and it completes meiosis II, yielding a secondary polar body and one large ovum
How many genomes are in a daughter cell?
1